Use of ATR inhibitor in combination with topoisomerase I inhibitor kills cancer cells by disabling DNA replication initiation and fork elongation

被引：0
|
作者：
Josse, R. [1 ]
Martin, S. E. [2 ]
Guha, R. [2 ]
Ormanoglu, P. [2 ]
Pfister, T. [3 ]
Morris, J. [4 ]
Doroshow, J. [4 ]
Pommier, Y. [1 ]
机构：
[1] NCI, Dev Therapeut Branch, Bethesda, MD 20892 USA
[2] NCATS, Div Preclin Innovat, Rockville, MD USA
[3] Leidos Biomed Res Inc, Lab Human Toxicol & Pharmacol, Frederick, MD USA
[4] DTP DCTD, Drug Synth & Chem Branch, Bethesda, MD USA
来源：
EUROPEAN JOURNAL OF CANCER | 2014年 / 50卷
关键词：
D O I：
10.1016/S0959-8049(14)70374-0
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
248
引用
收藏
页码：83 / 83
页数：1
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