Effectiveness of an Integrated Real-Time PCR Method for Detection of the Mycobacterium tuberculosis Complex in Smear-Negative Extrapulmonary Samples in an Area of Low Tuberculosis Prevalence

被引：78

作者：

Moure, Raquel ^{[1
]}

Martin, Rogelio ^{[1
,2
]}

Alcaide, Fernando ^{[1
,2
]}

机构：

[1] IDIBELL Bellvitge Hosp, Dept Microbiol, Lhospitalet De Llobregat, Barcelona, Spain

[2] Univ Barcelona, Dept Pathol & Expt Therapeut, Lhospitalet De Llobregat, Barcelona, Spain

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 02期

关键词：

XPERT MTB/RIF TEST; PLEURAL EFFUSION; DIAGNOSIS; RESISTANCE; TESTS;

D O I：

10.1128/JCM.06467-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Early extrapulmonary tuberculosis (EPTB) diagnosis is particularly difficult. Among 108 smear-negative extrapulmonary samples showing a positive culture for Mycobacterium tuberculosis complex (43 body fluids and 65 nonliquid specimens), 63 (58.3%) were positive with the Xpert MTB/RIF assay (GX). GX sensitivity was quite low for samples from sterile locations (especially for pleural fluids: 26.9%) but high for some nonliquid samples, like abscess aspirates (76.5%). In summary, GX may be a useful tool to be considered for EPTB diagnosis.

引用

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页码：513 / 515

页数：3

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