ExpressionPlot: a web-based framework for analysis of RNA-Seq and microarray gene expression data

被引：31
|
作者：
Friedman, Brad A. [1 ,2 ,3 ]
Maniatis, Tom [4 ]
机构：
[1] Harvard Univ, Dept Mol & Cell Biol, Cambridge, MA 02138 USA
[2] MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA
[3] Genentech Inc, Dept Bioinformat & Computat Biol, San Francisco, CA 94080 USA
[4] Columbia Univ Coll Phys & Surg, Dept Biochem & Mol Biophys, New York, NY 10032 USA
来源：
GENOME BIOLOGY | 2011年 / 12卷 / 07期
关键词：
DIFFERENTIAL EXPRESSION; NORMALIZATION;
D O I：
10.1186/gb-2011-12-7-r69
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
RNA-Seq and microarray platforms have emerged as important tools for detecting changes in gene expression and RNA processing in biological samples. We present ExpressionPlot, a software package consisting of a default back end, which prepares raw sequencing or Affymetrix microarray data, and a web-based front end, which offers a biologically centered interface to browse, visualize, and compare different data sets. Download and installation instructions, a user's manual, discussion group, and a prototype are available at http://expressionplot.com/.
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页数：11
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