ExpressionPlot: a web-based framework for analysis of RNA-Seq and microarray gene expression data

被引:31
|
作者
Friedman, Brad A. [1 ,2 ,3 ]
Maniatis, Tom [4 ]
机构
[1] Harvard Univ, Dept Mol & Cell Biol, Cambridge, MA 02138 USA
[2] MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA
[3] Genentech Inc, Dept Bioinformat & Computat Biol, San Francisco, CA 94080 USA
[4] Columbia Univ Coll Phys & Surg, Dept Biochem & Mol Biophys, New York, NY 10032 USA
来源
GENOME BIOLOGY | 2011年 / 12卷 / 07期
关键词
DIFFERENTIAL EXPRESSION; NORMALIZATION;
D O I
10.1186/gb-2011-12-7-r69
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
RNA-Seq and microarray platforms have emerged as important tools for detecting changes in gene expression and RNA processing in biological samples. We present ExpressionPlot, a software package consisting of a default back end, which prepares raw sequencing or Affymetrix microarray data, and a web-based front end, which offers a biologically centered interface to browse, visualize, and compare different data sets. Download and installation instructions, a user's manual, discussion group, and a prototype are available at http://expressionplot.com/.
引用
收藏
页数:11
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