Carbon nanotubes-based electrochemical (bio)sensors for biomarkers

被引：68
|
作者：
Rivas, Gustavo A. [1 ]
Rodriguez, Marcela C. [1 ]
Rubianes, Maria D. [1 ]
Gutierrez, Fabiana A. [1 ]
Eguilaz, Marcos [1 ]
Dalmasso, Pablo R. [2 ]
Primo, Emiliano N. [1 ]
Tettamanti, Cecilia [1 ]
Ramirez, Maria L. [1 ]
Montemerlo, Antonella [1 ]
Gallay, Pablo [1 ]
Parrado, Concepcion [3 ]
机构：
[1] Univ Nacl Cordoba, Fac Ciencias Quim, Dept Fisicoquim, INFIQC, Ciudad Univ, RA-5000 Cordoba, Argentina
[2] Univ Tecnol Nacl, Fac Reg Cordoba, Dept Ingn Quim, CIQA, RA-5016 Cordoba, Argentina
[3] Univ Complutense Madrid, Fac Ciencias Quim, Dept Quim Analit, E-28040 Madrid, Spain
来源：
APPLIED MATERIALS TODAY | 2017年 / 9卷
关键词：
Carbon nanotubes; Electrochemical (bio)sensors; Biomarkers; PROSTATE-SPECIFIC ANTIGEN; TUMOR-NECROSIS-FACTOR; SIGNAL AMPLIFICATION STRATEGY; LABEL-FREE IMMUNOSENSOR; CANCER BIOMARKER; SENSITIVE DETECTION; ALPHA-FETOPROTEIN; CARCINOEMBRYONIC ANTIGEN; CARDIAC BIOMARKERS; ULTRASENSITIVE DETECTION;
D O I：
10.1016/j.apmt.2017.10.005
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
This review is focused on the critical discussion about the most representative carbon nanotubes( CNTs)-based electrochemical (bio) sensors for the quantification of different biomarkers of clinical relevance reported in the period 2013-2017 (carcynoembryonic antigen, prostate specific antigen, alpha-fetoprotein, cytokines, cardiac biomarkers, insulin growth factor-1, beta-galactoside-alpha-2,6-sialyltransferase, DNA sequences, microRNAs, and dopamine). We concentrated our attention on the molecules used as (bio) recognition elements, the approaches for immobilizing these (bio) recognition molecules at the electrode surfaces, the strategies to generate the analytical signal (label-free or labeled), the analytical performance of the resulting (bio) sensors, and the role of CNTs in these different aspects. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：566 / 588
页数：23
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