AMN082, the first selective metabotropic glutaniate receptor subtype 7 agonist: Activation of receptor signaling via an allosteric site in the transmembrane domain

被引：0

作者：

Mitsukawa, K ^{[1
]}

Yamamoto, R ^{[1
]}

Nozulak, J ^{[1
]}

Ofner, S ^{[1
]}

Pescott, O ^{[1
]}

Lukic, S ^{[1
]}

Stoehr, N ^{[1
]}

Urwyler, S ^{[1
]}

Kuhn, R ^{[1
]}

Herrling, P ^{[1
]}

Cryan, JF ^{[1
]}

Flor, PJ ^{[1
]}

机构：

[1] Novartis Pharma AG, Novartis Inst BioMed Res, Neurosci Res, CH-4002 Basel, Switzerland

来源：

NEUROPHARMACOLOGY | 2005年 / 49卷

关键词：

D O I：

暂无

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

087

引用

页码：258 / 258

页数：1

共 42 条

[31] Agonist activation of the angiotensin II type 1 receptor alters the spatial proximity of transmembrane domain 7 to the ligand binding pocket
Fillion, Dany
Guillemette, Gaetan
Leduc, Richard
Escher, Emanuel
UNDERSTANDING BIOLOGY USING PEPTIDES, 2006, : 357 - +
[32] RETRACTED ARTICLE: Selective activation of the metabotropic glutamate receptor subtype 7 “mGluR7” attenuates acquisition, expression, and reinstatement of ethanol place preference
Amine Bahi
Psychopharmacology, 2011, 216 (4) : 601 - 601
[33] Blocking Metabotropic Glutamate Receptor Subtype 7 via the Venus Flytrap Domain Promotes a Chronic Stress-Resilient Phenotype in Mice
Estrela, Karolyne A. R.
Senninger, Lisa
Arndt, Josephine
Kabas, Melanie
Schmid, Ferdinand
Dillmann, Larissa
Auer, Sophia
Stepfer, Thomas
Flor, Peter J.
Uschold-Schmidt, Nicole
CELLS, 2022, 11 (11)
[34] NPS R-467 activation of chimeric calcium-metabotropic glutamate receptors and a calcium receptor deletion mutant indicates a site of action within the transmembrane domain of the calcium receptor.
Hammerland, LG
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Nemeth, EF
Fuller, FH
JOURNAL OF BONE AND MINERAL RESEARCH, 1996, 11 : P272 - P272
[35] Blocking Metabotropic Glutamate Receptor Subtype 7 (mGlu7) VIA THE Venus Flytrap Domain (VFTD) Inhibits Amygdala Plasticity, Stress, AND Anxiety-Related Behavior
Peterlik, D.
Gee, C. E.
Neuhaeuser, C.
Bouhelal, R.
Kaupmann, K.
Laue, G.
Uschold-Schmidt, N.
Feuerbach, D.
Zimmermann, K.
Ofner, S.
Cryan, J. F.
van der Putten, H.
Fendt, M.
Vranesic, I.
Glatthar, R.
Flor, P. J.
CURRENT NEUROPHARMACOLOGY, 2014, 12 : 51 - 52
[36] Blocking Metabotropic Glutamate Receptor Subtype 7 ( mGlu7) via the Venus Flytrap Domain ( VFTD) Inhibits Amygdala Plasticity, Stress, and Anxiety-related Behavior
Gee, Christine E.
Peterlik, Daniel
Neuhaeuser, Christoph
Bouhelal, Rochdi
Kaupmann, Klemens
Laue, Grit
Uschold-Schmidt, Nicole
Feuerbach, Dominik
Zimmermann, Kaspar
Ofner, Silvio
Cryan, John F.
van der Putten, Herman
Fendt, Markus
Vranesic, Ivo
Glatthar, Ralf
Flor, Peter J.
JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (16) : 10975 - 10987
[37] Selective Activation of Alpha 7 Nicotinic Receptor Antagonizes Apoptosis in Renal Cells via Nrf2 Signaling
Huang, Tao
Dong, Zhen
Cao, Yanwei
Wang, Qinghai
Jin, Xunbo
ANALYTICAL AND QUANTITATIVE CYTOPATHOLOGY AND HISTOPATHOLOGY, 2020, 42 (03): : 69 - 76
[38] Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα13 and β-arrestin-2
Jenkins, Laura
Alvarez-Curto, Elisa
Campbell, Kate
de Munnik, Sabrina
Canals, Meritxell
Schlyer, Sabine
Milligan, Graeme
BRITISH JOURNAL OF PHARMACOLOGY, 2011, 162 (03) : 733 - 748
[39] SELECTIVE COUPLING OF PROSTAGLANDIN-E RECEPTOR EP3D TO MULTIPLE G-PROTEINS DEPENDING ON INTERACTION OF THE CARBOXYLIC-ACID OF AGONIST AND ARGININE RESIDUE OF 7TH TRANSMEMBRANE DOMAIN
NEGISHI, M
HARAZONO, A
SUGIMOTO, Y
HAZATO, A
KUROZUMI, S
ICHIKAWA, A
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1995, 212 (02) : 279 - 285
[40] SELECTIVE COUPLING OF PROSTAGLANDIN-E RECEPTOR EP3D TO G(I) AND G(S) THROUGH INTERACTION OF ALPHA-CARBOXYLIC ACID OF AGONIST AND ARGININE RESIDUE OF 7TH TRANSMEMBRANE DOMAIN
NEGISHI, M
IRIE, A
SUGIMOTO, Y
NAMBA, T
ICHIKAWA, A
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (27) : 16122 - 16127

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