Microwave-assisted solvent-free synthesis of the substituted spiroindolinonaphth[2,1-b][1,4]oxazines

被引：8
|
作者：
Koshkin, AV
Fedorova, OA
Lokshin, V
Guglielmetti, R
Hamelin, J
Texier-Boullet, F
Gromov, SP
机构：
[1] Russian Acad Sci, Ctr Photochem, Moscow 119421, Russia
[2] Univ Rennes 1, Rennes, France
[3] Univ Mediterranee, Fac Sci Luminy, Marseille, France
来源：
SYNTHETIC COMMUNICATIONS | 2004年 / 34卷 / 02期
基金：
俄罗斯基础研究基金会;
关键词：
microwave irradiation; spirooxazines; solvent-free synthesis;
D O I：
10.1081/SCC-120027269
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of the substituted spiroindolinonaphth[2,1-b][1,4]oxazines 3a-e is developed through the condensation of 2-methylene-1,3,3-trimethylindoline derivatives and 1-nitroso-2-naphthol under microwave irradiation. In the same conditions, in presence of morpholine the 6'-morpholinosubstituted compounds 4a, b, d, e are formed. The main advantages of the method are the short reaction time, solvent-free reaction condition, cleaner reaction products and the higher product yields in comparison with known methods of synthesis.
引用
收藏
页码：315 / 322
页数：8
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