Complete Responses in Relapsed/Refractory Acute Myeloid Leukemia (AML) Patients on a Weekly Dosing Schedule of XmAb14045, a CD123 x CD3 T Cell-Engaging Bispecific Antibody: Initial Results of a Phase 1 Study

被引:46
|
作者
Ravandi, Farhad [1 ]
Bashey, Asad [2 ]
Foran, James M. [3 ]
Stock, Wendy [4 ]
Mawad, Raya [5 ]
Blum, William [6 ]
Saville, M. Wayne [7 ]
Johnson, Chelsea M. [7 ]
Vanasse, K. Gary J. [8 ]
Ly, Thomas [7 ]
Kantarjian, Hagop M. [1 ]
Bhatnagar, Bhavana [9 ]
Takahashi, Koichi [1 ]
Mims, Alice S. [10 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA
[2] Northside Hosp, Acute Leukemia & BMT Program, Atlanta, GA USA
[3] Mayo Clin Florida, Div Hematol & Med Oncol, Dept Med, Jacksonville, FL USA
[4] Univ Chicago, Dept Med, Sect Hematol Oncol, 5841 S Maryland Ave, Chicago, IL 60637 USA
[5] Swedish Canc Inst, Ctr Blood Disorders & Stem Cell Transplantat, Seattle, WA USA
[6] Emory Univ, Dept Hematol & Oncol, Winship Canc Inst, Atlanta, GA 30322 USA
[7] Xencor Inc, San Diego, CA USA
[8] Novartis Inst Biomed Res, Cambridge, MA USA
[9] Ohio State Univ, Div Hematol, Columbus, OH 43210 USA
[10] Med Univ South Carolina, Div Hematol, Columbus, OH USA
关键词
D O I
10.1182/blood-2018-99-119786
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
763
引用
收藏
页数:3
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