Simple alumina-mediated synthesis of 2-(2-hydroxypropan-2-yl)benzofuran-3(2H)-ones

被引：5
|
作者：
Fang, Lizhen [1 ]
Han, Lili [1 ]
Liu, Saisai [1 ]
Li, Huanhuan [1 ]
机构：
[1] Xinxiang Med Univ, Sch Pharm, Xinxiang 453003, Henan, Peoples R China
来源：
TETRAHEDRON LETTERS | 2016年 / 57卷 / 30期
基金：
中国国家自然科学基金;
关键词：
Aldol reaction; 2-(2-Hydroxypropan-2-yl)benzofuran-3(2H)-one; Alumina; DERIVATIVES; KETONES; ISATIN;
D O I：
10.1016/j.tetlet.2016.06.058
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In this study, the Aldol condensation between benzofuran-3(2H)-ones and ketones or aldehydes mediated by alumina was developed. This simple protocol facilitated the synthesis of various 2-(2-hydroxypropan-2-yl)benzofuran-3(2H)-ones in moderate-to-high yields under mild conditions. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3315 / 3317
页数：3
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