New dammarane-type triterpenoid glycosides from Gynostemma burmanicum

被引:3
|
作者
Than Thi Kieu My [1 ]
Pham Thanh Ky [1 ]
Pham Thanh Binh [2 ]
Nguyen Phuong Thao [2 ]
Nguyen Tien Dat [3 ]
机构
[1] Hanoi Univ Pharm, Dept Pharmacognosy, Hanoi, Vietnam
[2] Vietnam Acad Sci & Technol VAST, Inst Marine Biochem, Dept Bioact Prod, Hanoi, Vietnam
[3] VAST, Lab Biochem Res & Applicat, Ctr Res & Technol Transfer, Hanoi, Vietnam
关键词
Gynostemma burmanicum; Cucurbitaceae; dammarane saponin; CONSTITUENTS; SAPONINS; LEAVES; GINSENG; MAKINO;
D O I
10.1080/14786419.2018.1527831
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The chemical composition of Gynostemma burmanicum King ex Chakrav. was investigated for the first time in this study. Nine dammarane glycosides (1-9) were isolated from the EtOH extract of the aerial parts of G. burmanicum. Their structures were elucidated by 1D and 2D NMR spectroscopic interpretation as well as by chemical studies. The new compounds were 3 beta,20S-dihydroxydammar-24-ene-3-O-beta-D-glucopyranosyl-20-O-[beta-D-xylopyranosyl-(1 -> 6)-beta-D-glucopyranoside] (1), 3 beta,12 beta,20S-trihydroxydammar-24-ene-3-O-beta-D-xylopyranosyl-20-O-[beta-D-xylopyranosyl-(1 -> 6)-beta-D-glucopyranoside] (2), and 12-oxo-3 beta,20S-dihydroxydammar-24-ene-3-O-[beta-D-glucopyranosyl(1 -> 2)-beta-D-glucopyranosyl]-20-O-[beta-D-xylopyranosyl-(1 -> 6)-beta-D-glucopyranoside] (3).
引用
收藏
页码:217 / 224
页数:8
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