Linezolid resistance in a clinical isolate of Staphylococcus aureus

被引：838
|
作者：
Tsiodras, S
Gold, HS
Sakoulas, G
Eliopoulos, GM
Wennersten, C
Venkataraman, L
Moellering, RC
Ferraro, MJ
机构：
[1] Massachusetts Gen Hosp, Dept Pathol, Clin Microbiol Labs, Boston, MA 02114 USA
[2] Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA
[3] Beth Israel Deaconess Med Ctr, Dept Pathol, Boston, MA 02215 USA
[4] Massachusetts Gen Hosp, Dept Med, Boston, MA 02114 USA
[5] Harvard Univ, Sch Med, Boston, MA USA
来源：
LANCET | 2001年 / 358卷 / 9277期
关键词：
D O I：
10.1016/S0140-6736(01)05410-1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The new oxazolidinone antimicrobial, linezolid, has been approved for the treatment of infections caused by various gram-positive bacteria, including meticillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Although instances of linezolid resistance in VRE have been reported, resistance has not been encountered among clinical isolates of S aureus. We have characterised an MRSA isolate resistant to linezolid that was recovered from a patient treated with this agent for dialysis-associated peritonitis.
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页码：207 / 208
页数：2
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