Linezolid resistance in a clinical isolate of Staphylococcus aureus

被引：838
|
作者：
Tsiodras, S
Gold, HS
Sakoulas, G
Eliopoulos, GM
Wennersten, C
Venkataraman, L
Moellering, RC
Ferraro, MJ
机构：
[1] Massachusetts Gen Hosp, Dept Pathol, Clin Microbiol Labs, Boston, MA 02114 USA
[2] Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA
[3] Beth Israel Deaconess Med Ctr, Dept Pathol, Boston, MA 02215 USA
[4] Massachusetts Gen Hosp, Dept Med, Boston, MA 02114 USA
[5] Harvard Univ, Sch Med, Boston, MA USA
来源：
LANCET | 2001年 / 358卷 / 9277期
关键词：
D O I：
10.1016/S0140-6736(01)05410-1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The new oxazolidinone antimicrobial, linezolid, has been approved for the treatment of infections caused by various gram-positive bacteria, including meticillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Although instances of linezolid resistance in VRE have been reported, resistance has not been encountered among clinical isolates of S aureus. We have characterised an MRSA isolate resistant to linezolid that was recovered from a patient treated with this agent for dialysis-associated peritonitis.
引用
下载
收藏
页码：207 / 208
页数：2
相关论文
共 50 条
  • [21] Clinical characteristics of linezolid-resistant Staphylococcus aureus infections
    Peeters, MJ
    Sarria, JC
    AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2005, 330 (02): : 102 - 104
  • [22] Inactivation of the Indigenous Methyltransferase RlmN in Staphylococcus aureus Increases Linezolid Resistance
    LaMarre, Jacqueline M.
    Howden, Benjamin P.
    Mankin, Alexander S.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2011, 55 (06) : 2989 - 2991
  • [23] Vancomycin and linezolid resistance among multidrug-resistant Staphylococcus aureus clinical isolates and interaction with neutrophils
    Al-Bdery, Alaa Shahid Jassim
    Mohammad, Ghaidaa Jihadi
    Hussen, Bashdar
    GENE REPORTS, 2020, 21
  • [24] Linezolid-resistance Staphylococcus aureus - Prevalence, Emerging Resistance Mechanisms, Challenges and Perspectives
    Rafique, Hassan
    Hussain, Nazim
    Saeed, Muhammad Usama
    Iqbal, Hafiz M. N.
    Azim, Gulfam
    Bilal, Muhammad
    JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2022,
  • [25] Linezolid-resistance Staphylococcus aureus - Prevalence, Emerging Resistance Mechanisms, Challenges and Perspectives
    Rafique, Hassan
    Hussain, Nazim
    Saeed, Muhammad Usama
    Iqbal, Hafiz M. N.
    Azim, Gulfam
    Bilal, Muhammad
    JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2022, 16 (03): : 1492 - 1505
  • [26] Characterization of the role of IS256 in the development of intermediate vancomycin resistance in a clinical Staphylococcus aureus isolate
    Nagel, M.
    Jansen, A.
    Tuerck, M.
    Bierbaum, G.
    INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2007, 297 : 65 - 66
  • [27] Resistance to Linezolid Is Mediated by the cfr Gene in the First Report of an Outbreak of Linezolid-Resistant Staphylococcus aureus
    Morales, Gracia
    Picazo, Juan J.
    Baos, Elvira
    Candel, Francisco J.
    Arribi, Ana
    Pelaez, Beatriz
    Andrade, Raquel
    de la Torre, Maria-Angeles
    Fereres, Jose
    Sanchez-Garcia, Miguel
    CLINICAL INFECTIOUS DISEASES, 2010, 50 (06) : 821 - 825
  • [28] Linezolid-resistant Staphylococcus capitis isolate
    Ibrahim, R.
    Waked, R.
    Choucair, J.
    Aubry, A.
    Laurent, F.
    Simoes, P. Martins
    Dupieux-Chabert, C.
    Haddad, E.
    INFECTIOUS DISEASES NOW, 2022, 52 (03): : 176 - 177
  • [29] Phenotypic and Genotypic Analysis of Gentamicin, Penicillin, Methicillin, Vancomycin, Linezolid and Tetracycline Resistance in Clinical Isolates of Staphylococcus aureus
    Orhan, Zerife
    Kayis, Arzu
    Kaya, Esra
    Aral, Murat
    KSU TARIM VE DOGA DERGISI-KSU JOURNAL OF AGRICULTURE AND NATURE, 2018, 21 (06): : 957 - 965
  • [30] LinezolidEmergence of linezolid resistance in Staphylococcus aureus and Enterococcus faecium infections: case report
    Reactions Weekly, 2011, 1339 (1) : 26 - 26
12345