Amyloid-β and tau PET scans predict clinical progression in cognitively unimpaired people

被引：2

作者：

Ossenkoppele, Rik ^{[1
]}

Hansson, Oskar ^{[1
]}

Hampel, Harald ^{[2
]}

机构：

[1] Lund Univ, Clin Memory Res Unit, Lund, Sweden

[2] Eisai Inc, Nutley, NJ USA

来源：

NATURE MEDICINE | 2022年 / 28卷 / 11期

关键词：

D O I：

10.1038/s41591-022-02071-z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Evidence — provided by a combination of amyloid-β and tau PET examinations — of advanced Alzheimer’s disease pathological changes in the brain in cognitively unimpaired individuals is strongly associated with short-term (3–5 years) cognitive decline. Thus, amyloid-β and tau PET have high clinical relevance.

引用

页码：2267 / 2268

页数：2

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