Design of the "Thorough QT Study''

被引:5
|
作者
Darpo, B. [1 ]
Sager, P. [1 ]
机构
[1] AstraZeneca LP, CV Res, Wilmington, DE USA
关键词
D O I
10.1038/sj.clpt.6100294
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:528 / 529
页数:3
相关论文
共 50 条
  • [31] Evaluation of the Effect of Ruxolitinib on Cardiac Repolarization: A Thorough QT Study
    Punwani, Naresh
    Yeleswaram, Swamy
    Chen, Xuejun
    Bowman, Jill
    Soloviev, Maxim
    Williams, William
    [J]. CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2014, 3 (03): : 207 - 214
  • [32] No QTc Prolongation with Semaglutide: A Thorough QT Study in Healthy Subjects
    Valentin Demmel
    Anne Sandberg-Schaal
    Jacob B. Jacobsen
    Georg Golor
    Jonas Pettersson
    Anne Flint
    [J]. Diabetes Therapy, 2018, 9 : 1441 - 1456
  • [33] Dapagliflozin Was Not Observed To Prolong the QTc in a Thorough QT/QTc Study
    Carlson, Glenn F.
    Tou, Conrad K. P.
    Parikh, Shamik
    Birmingham, Bruce K.
    Butler, Kathleen
    [J]. DIABETES, 2009, 58 : A129 - A129
  • [34] Thorough QT study to evaluate the effect of fesoterodine on cardiac repolarization
    Malhotra, B.
    Wood, N.
    Holbrook, M.
    Sachse, R.
    Scholfield, D.
    Orri, M.
    [J]. FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2008, 22 : 68 - 68
  • [35] PK/PD modeling of a clazosentan thorough QT study with hysteresis in concentration-QT and RR-QT
    Henrich, Andrea
    Juif, Pierre-Eric
    Dingemanse, Jasper
    Krause, Andreas
    [J]. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2021, 48 (02) : 213 - 224
  • [36] PK/PD modeling of a clazosentan thorough QT study with hysteresis in concentration-QT and RR-QT
    Andrea Henrich
    Pierre-Eric Juif
    Jasper Dingemanse
    Andreas Krause
    [J]. Journal of Pharmacokinetics and Pharmacodynamics, 2021, 48 : 213 - 224
  • [37] Application of Trial Simulation in the Design of a Prospective Study for Concentration-QTc Analysis in Support of a Thorough QT Study Waiver
    Peijuan Zhu
    Chyi-Hung Hsu
    Chuanpu Hu
    Peggy Wong
    Sherwin K. B. Sy
    Partha Nandy
    Honghui Zhou
    [J]. The AAPS Journal, 22
  • [38] Application of Trial Simulation in the Design of a Prospective Study for Concentration-QTc Analysis in Support of a Thorough QT Study Waiver
    Zhu, Peijuan
    Hsu, Chyi-Hung
    Hu, Chuanpu
    Wong, Peggy
    Sy, Sherwin K. B.
    Nandy, Partha
    Zhou, Honghui
    [J]. AAPS JOURNAL, 2020, 22 (05):
  • [39] Dabigatran Does Not Prolong the QT Interval with Supratherapeutic Exposure: a Thorough QT Study in Healthy Subjects
    Arne Ring
    Karin Rathgen
    Joachim Stangier
    Paul Reilly
    Andreas Clemens
    Jeffrey Friedman
    [J]. Clinical Drug Investigation, 2013, 33 : 333 - 342
  • [40] Dabigatran Does Not Prolong the QT Interval with Supratherapeutic Exposure: a Thorough QT Study in Healthy Subjects
    Ring, Arne
    Rathgen, Karin
    Stangier, Joachim
    Reilly, Paul
    Clemens, Andreas
    Friedman, Jeffrey
    [J]. CLINICAL DRUG INVESTIGATION, 2013, 33 (05) : 333 - 342