Novel application of Leuckart-Wallach reaction for synthesis of tetrahydro-1,4-benzodiazepin-5-ones library

被引：55
|
作者：
Lee, Sung-Chan [1 ]
Park, Seung Bum [1 ]
机构：
[1] Seoul Natl Univ, Dept Chem, Seoul, South Korea
来源：
CHEMICAL COMMUNICATIONS | 2007年 / 36期
关键词：
PHARMACOLOGICAL ACTIVITY; INHIBITORS; DERIVATIVES; BENZODIAZEPINE; ANTHRAMYCIN; DESIGN;
D O I：
10.1039/b709768a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel and efficient strategy has been developed to synthesize privileged tetrahydro-1,4-benzodiazepines with excellent yields and purities; this synthetic pathway was established by the revitalization of the Leuckart-Wallach(LW) reaction via solidphase synthesis.
引用
收藏
页码：3714 / 3716
页数：3
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