The cost and impact of compulsivity: A research perspective

被引：51

作者：

Hollander, Eric ^{[1
,2
]}

Doernberg, Ellen ^{[1
,2
]}

Shavitt, Roseli ^{[3
]}

Waterman, Richard J. ^{[4
,5
]}

Soreni, Noam ^{[6
]}

Veltman, Dick J. ^{[7
]}

Sahakian, Barbara J. ^{[8
,9
]}

Fineberg, Naomi A. ^{[4
,5
]}

机构：

[1] Albert Einstein Coll Med, Dept Psychiat & Behav Sci, Anxiety & Depress Program, Autism & Obsess Compuls Spectrum Program, Bronx, NY 10467 USA

[2] Montefiore Med Ctr, 111 E 210th St, Bronx, NY 10467 USA

[3] Univ Sao Paulo, Sch Med, Dept Psychiat, Sao Paulo, Brazil

[4] Hertfordshire Partnership Univ NHS Fdn Trust, Highly Specialized Obsess Compuls Disorder & Bod, Rosanne House,Pkwy, Welwyn Garden City AL8 6HG, Herts, England

[5] Univ Hertfordshire, Coll Lane, Hatfield AL10 9AB, Herts, England

[6] McMaster Univ, St Josephs Healthcare, Anxiety Treatment & Res Ctr, Pediat OCD Consultat Team, 100 West 5th St, Hamilton, ON L8N 3K7, Canada

[7] Vrije Univ Amsterdam, Med Ctr, De Boelelaan 1117, NL-1081 HV Amsterdam, Netherlands

[8] Univ Cambridge, Sch Clin Med, Dept Psychiat, Cambridge CB2 2QQ, England

[9] Addenbrookes Hosp, MRC Welcome Trust Behav & Clin Neurosci Inst, Cambridge CB2 2QQ, England

来源：

EUROPEAN NEUROPSYCHOPHARMACOLOGY | 2016年 / 26卷 / 05期

关键词：

Compulsivity; OCRDs; OCD; Cost; Diagnosis; Treatment; QUALITY-OF-LIFE; REPETITIVE BEHAVIORS; MENTAL-DISORDERS; DRUG-ADDICTION; BRAIN; BURDEN; PREVALENCE; CHILDREN; FAMILY; COMORBIDITY;

D O I：

10.1016/j.euroneuro.2016.02.006

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Compulsivity is the defining feature of various psychiatric disorders including Obsessive Compulsive Related Disorders (OCRDs), and other compulsive, impulsive, and addictive disorders. These disorders are disabling, chronic conditions with an early onset and high rates of comorbidity, misdiagnoses, and delay in treatment onset. Disorders of compulsivity are responsible for considerable socioeconomic burden to society. We review the costs and impacts of compulsivity. In order to facilitate earlier diagnosis and targeted treatments, we examine the overlapping mechanisms that underlie compulsivity. We reconceptualize psychiatric disorders based on core features of compulsivity, highlight challenges in harmonizing research in children and adults, describe newer research methodologies, and point to future directions that can impact the costs and impact of disorders of compulsivity. (C) 2016 Elsevier B.V. and ECNP. All rights reserved.

引用

页码：800 / 809

页数：10

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