Purification, chemical characterization and in vitro antioxidant activities of alkali-extracted polysaccharide fractions isolated from the fruits of Schisandra chinensis

被引：0
|
作者：
Sheng, Yu [1 ]
Liu, Yang [1 ]
Huang, Xiaodong [2 ]
Yuan, Guangxin [3 ]
Guan, Ming [1 ]
机构：
[1] Jilin Univ, Sch Pharmaceut Sci, Changchun 130021, Peoples R China
[2] Jilin Med Coll, Jilin 132013, Jilin, Peoples R China
[3] Beihua Univ, Pharmaceut Coll, Jilin 132013, Jilin, Peoples R China
来源：
JOURNAL OF MEDICINAL PLANTS RESEARCH | 2011年 / 5卷 / 24期
关键词：
Schisandra chinensis; polysaccharide; antioxidant activity;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The alkali-extracted crude polysaccharide was extracted from the fruits of Schisandra chinensis, and further purified by DEAE-cellulose and Sepharose CL-6B chromatography, giving three polysaccharide fractions coded as ASPS-a-1, ASPS-b-2 and ASPS-b-3. In this study, their chemical and physical characteristics of polysaccharide fractions and antioxidant capacity, including scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, chelating ability, hydroxyl radicals and superoxide radicals, were evaluated. The results showed that ASPS-b-3 exhibited significantly antioxidant activity at a concentration-dependent manner. The alkali-extracted polysaccharide fraction can be developed to be new antioxidant drug.
引用
收藏
页码：5881 / 5888
页数：8
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