Purification, chemical characterization and in vitro antioxidant activities of alkali-extracted polysaccharide fractions isolated from the fruits of Schisandra chinensis

被引：0

作者：

Sheng, Yu ^{[1
]}

Liu, Yang ^{[1
]}

Huang, Xiaodong ^{[2
]}

Yuan, Guangxin ^{[3
]}

Guan, Ming ^{[1
]}

机构：

[1] Jilin Univ, Sch Pharmaceut Sci, Changchun 130021, Peoples R China

[2] Jilin Med Coll, Jilin 132013, Jilin, Peoples R China

[3] Beihua Univ, Pharmaceut Coll, Jilin 132013, Jilin, Peoples R China

来源：

JOURNAL OF MEDICINAL PLANTS RESEARCH | 2011年 / 5卷 / 24期

关键词：

Schisandra chinensis; polysaccharide; antioxidant activity;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The alkali-extracted crude polysaccharide was extracted from the fruits of Schisandra chinensis, and further purified by DEAE-cellulose and Sepharose CL-6B chromatography, giving three polysaccharide fractions coded as ASPS-a-1, ASPS-b-2 and ASPS-b-3. In this study, their chemical and physical characteristics of polysaccharide fractions and antioxidant capacity, including scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, chelating ability, hydroxyl radicals and superoxide radicals, were evaluated. The results showed that ASPS-b-3 exhibited significantly antioxidant activity at a concentration-dependent manner. The alkali-extracted polysaccharide fraction can be developed to be new antioxidant drug.

引用

页码：5881 / 5888

页数：8

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