A key role for IL-13 signaling via the type 2 IL-4 receptor in atopic dermatitis

被引:0
|
作者
Munitz, Ariel [1 ]
Bitton, Almog [1 ]
Avlas, Shmuel [1 ]
Reichman, Hadar [1 ]
Itan, Michal [1 ]
Karo-Atar, Danielle [1 ]
Azouz, Nurit [2 ]
Rozenberg, Perri [1 ]
Nahari, Limor
Rothenberg, Marc
Benhar, Itai [1 ]
机构
[1] Tel Aviv Univ, Tel Aviv, Israel
[2] Cincinnati Childrens Hosp Med Ce, Cincinnati, OH USA
关键词
D O I
暂无
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
490
引用
收藏
页码:AB153 / AB153
页数:1
相关论文
共 50 条
  • [31] Immunohistochemical Characterization of the IL-13:IL-4 Receptor α Axis in the Skin of Adult Patients with Moderate to Severe Atopic Dermatitis and Healthy Controls
    Miranda, Elena
    Roberts, Jennifer
    Novick, Steven
    Lapointe, Jean-Martin
    Bruijnzeel-Koomen, Carla
    Thijs, JudithL
    Sleeman, Matthew A.
    May, Richard D.
    Hijnen, DirkJan
    Strickland, Ian
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021, 141 (02) : 440 - 443
  • [32] Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma
    Agrawal, Swati
    Townley, Robert G.
    EXPERT OPINION ON BIOLOGICAL THERAPY, 2014, 14 (02) : 165 - 181
  • [33] Different effects of combined blockade of IL-4/IL-13 and selective inhibition of IL-13 in in vitro model systems for atopic dermatitis with allergen stimulated lymphocytes
    Honstein, T.
    Evers, S.
    Roesner, L. M.
    Zeitvogel, J.
    Werfel, T.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021, 141 (05) : S3 - S3
  • [34] The IL-4/IL-13 signaling axis promotes prostatic fibrosis
    D'Arcy, Quentin
    Gharaee-Kermani, Mehrnaz
    Zhilin-Roth, Alisa
    Macoska, Jill A.
    PLOS ONE, 2022, 17 (10):
  • [35] On the Role IL-4/IL-13 Heteroreceptor Plays in Regulation of Type 1 Diabetes
    Ukah, Tobechukwu K.
    Cattin-Roy, Alexis N.
    Chen, Weirong
    Miller, Mindy M.
    Barik, Subhasis
    Zaghouani, Habib
    JOURNAL OF IMMUNOLOGY, 2017, 199 (03): : 894 - 902
  • [36] IL-4 receptor α polymorphisms are predictors of a pharmacogenetic response to a novel IL-4/IL-13 antagonist
    Slager, Rebecca E.
    Hawkins, Gregory A.
    Ampleford, Elizabeth J.
    Bowden, Alexandra
    Stevens, Lauren E.
    Morton, Matthew T.
    Tomkinson, Adrian
    Wenzel, Sally E.
    Longphre, Malinda
    Bleecker, Eugene R.
    Meyers, Deborah A.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 126 (04) : 875 - 878
  • [37] Structure, binding, and antagonists in the IL-4/IL-13 receptor system
    Mueller, TD
    Zhang, JL
    Sebald, W
    Duschl, A
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2002, 1592 (03): : 237 - 250
  • [38] Structural similarity of IL-13 and IL-4
    Tang, JCT
    Cannon-Carlson, S
    Varnerin, J
    Tsarbopoulos, A
    Wylie, D
    FASEB JOURNAL, 1997, 11 (09): : A1361 - A1361
  • [39] IL-13 antagonists in the treatment of atopic dermatitis
    Tubau, Carla
    Puig, Lluis
    IMMUNOTHERAPY, 2021, 13 (04) : 327 - 344
  • [40] IL-4 receptor α is an important modulator of IL-4 and IL-13 receptor binding:: Implications for the development of therapeutic targets
    Andrews, Allison-Lynn
    Holloway, John W.
    Holgate, Stephen T.
    Davies, Donna E.
    JOURNAL OF IMMUNOLOGY, 2006, 176 (12): : 7456 - 7461