IL-4 receptor α polymorphisms are predictors of a pharmacogenetic response to a novel IL-4/IL-13 antagonist

被引：32
|
作者：
Slager, Rebecca E. [1 ]
Hawkins, Gregory A. [1 ]
Ampleford, Elizabeth J. [1 ]
Bowden, Alexandra [2 ]
Stevens, Lauren E. [2 ]
Morton, Matthew T. [2 ]
Tomkinson, Adrian [2 ]
Wenzel, Sally E. [3 ]
Longphre, Malinda [2 ]
Bleecker, Eugene R. [1 ]
Meyers, Deborah A. [1 ]
机构：
[1] Wake Forest Univ, Bowman Gray Sch Med, Ctr Genom & Personalized Med Res, Winston Salem, NC 27106 USA
[2] Aerovance, Berkeley, CA USA
[3] Univ Pittsburgh, Med Ctr, Div Pulm Allergy & Crit Care Med, Pittsburgh, PA USA
来源：
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2010年 / 126卷 / 04期
关键词：
DUTCH POPULATION; ASTHMA; ASSOCIATION; ATOPY; GENE;
D O I：
10.1016/j.jaci.2010.08.001
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
[No abstract available]
引用
收藏
页码：875 / 878
页数：5
相关论文
共 50 条
  • [1] The evolution of IL-4 and IL-13 and their receptor subunits
    Wang, Tiehui
    Secombes, Christopher J.
    [J]. CYTOKINE, 2015, 75 (01) : 8 - 13
  • [2] Distinct roles for IL-13 and IL-4 via IL-13 receptor α1 and the type II IL-4 receptor in asthma pathogenesis
    Munitz, A.
    Brandt, E. B.
    Mingler, M.
    Finkelmant, F. D.
    Rothenberg, M. E.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (20) : 7240 - 7245
  • [3] Polymorphisms in the IL-13 and IL-4 receptor alpha genes and allergic rhinitis
    Jeong Joong Kim
    Jung Youl Min
    Jae Hoon Lee
    [J]. European Archives of Oto-Rhino-Laryngology, 2007, 264 : 395 - 399
  • [4] Polymorphisms in the IL-13 and IL-4 receptor alpha genes and allergic rhinitis
    Kim, Jeong Joong
    Min, Jung Youl
    Lee, Jae Hoon
    [J]. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2007, 264 (04) : 395 - 399
  • [5] Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma
    Agrawal, Swati
    Townley, Robert G.
    [J]. EXPERT OPINION ON BIOLOGICAL THERAPY, 2014, 14 (02) : 165 - 181
  • [6] Structural similarity of IL-13 and IL-4
    Tang, JCT
    Cannon-Carlson, S
    Varnerin, J
    Tsarbopoulos, A
    Wylie, D
    [J]. FASEB JOURNAL, 1997, 11 (09): : A1361 - A1361
  • [7] Mast cell production and response to IL-4 and IL-13
    McLeod, Jamie J. A.
    Baker, Bianca
    Ryan, John J.
    [J]. CYTOKINE, 2015, 75 (01) : 57 - 61
  • [8] IL-4 receptor α is an important modulator of IL-4 and IL-13 receptor binding:: Implications for the development of therapeutic targets
    Andrews, Allison-Lynn
    Holloway, John W.
    Holgate, Stephen T.
    Davies, Donna E.
    [J]. JOURNAL OF IMMUNOLOGY, 2006, 176 (12): : 7456 - 7461
  • [9] Structure, binding, and antagonists in the IL-4/IL-13 receptor system
    Mueller, TD
    Zhang, JL
    Sebald, W
    Duschl, A
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2002, 1592 (03): : 237 - 250
  • [10] ACTIVATION OF HUMAN NEUTROPHILS BY IL-4 AND IL-13
    BEAULIEU, AD
    PAQUIN, R
    GIRARD, D
    [J]. ARTHRITIS AND RHEUMATISM, 1995, 38 (09): : 713 - 713
12345