Efficient synthesis of novel benzo-[e]-[1,4]-diazepine derivatives

被引：11

作者：

Messeri, T ^{[1
]}

Pentassuglia, G ^{[1
]}

Di Fabio, R ^{[1
]}

机构：

[1] Glaxo Wellcome SpA, Med Res Ctr, I-37135 Verona, Italy

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 18期

关键词：

glycine antagonists; synthesis; benzo-[e]-[1,4]-diazepines;

D O I：

10.1016/S0040-4039(01)00402-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Following two efficient synthetic routes a novel series of benzo-[e]-[1,4]-diazepine derivatives, bearing an unusual Z exo-methylencarbamoyl side chain at the C-5 position, have been prepared to identify new antagonists of the glycine binding site associated with NMDA receptor. (C) 2001 Published by Elsevier Science Ltd.

引用

页码：3227 / 3230

页数：4

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