A novel palladium-catalyzed coupling of thiol esters with 1-alkynes

被引：0
|
作者：
Tokuyama, H [1 ]
Miyazaki, T [1 ]
Yokoshima, S [1 ]
Fukuyama, T [1 ]
机构：
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan
来源：
SYNLETT | 2003年 / 10期
关键词：
1-alkynyl ketones; thiol esters; Sonogashira-type coupling reaction; palladium; copper;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new method for synthesizing alpha,beta-acetylenic ketones by palladium-mediated coupling of thiol esters with I -alkynes is described. The reaction could be applied to coupling of thiol esters bearing various functional groups, such as aromatic bromides, and ketones, with functionalized terminal acetylenes.
引用
收藏
页码：1512 / 1514
页数：3
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