Rapidly progressing bilateral cataracts in a patient with beta thalassemia and pellagra

被引：8
|
作者：
Athanasiadis, Ioannis
Konstantinidis, Aristeidis
Kyprianou, Ioannis
Robinson, Rosemary
Moschou, Vaia
Kouzi-Koliakos, Kokkona
机构：
[1] Coventry & Warwickshire Univ Hosp NHS Trust, Dept Ophthalmol, Walsgrave Hosp, Coventry, W Midlands, England
[2] Aristotle Univ Thessaloniki, AHEPA Univ Hosp, Thessaloniki, Greece
来源：
JOURNAL OF CATARACT AND REFRACTIVE SURGERY | 2007年 / 33卷 / 09期
关键词：
D O I：
10.1016/j.jcrs.2007.05.011
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Soon after the diagnosis of pellagra in a 20-year-old patient with beta thalassemia, bilateral intumescent cataracts rapidly developed. We believe the patient's crystalline lenses were at an increased oxidative state due to iron overload from the thalassemia. Depletion of the lens epithelial cells of an important antioxidative agent (glutathione) as a result of niacin (vitamin B3) deficiency due to pellagra reduced the antioxidative capacity of the lenses. The oxidative damage led to rapid development of cataracts.
引用
收藏
页码：1659 / 1661
页数：3
相关论文
共 50 条
  • [41] RAPIDLY PROGRESSING QUADRIPARESIS SECONDARY TO CERVICAL PYOGENIC SPONDYLITIS IN A PATIENT WITH KLIPPEL-FEIL SYNDROME
    BABA, H
    MAEZAWA, Y
    KOKUBO, Y
    KAWAHARA, N
    JOURNAL OF SPINAL DISORDERS, 1995, 8 (02): : 151 - 156
  • [42] An HIV-infected patient with associated, lethal rhinopharyngeal actinomycosis and a rapidly progressing local adenocarcinoma
    Roberto Manfredi
    Sergio Sabbatani
    Ciro Fulgaro
    Retrovirology, 7
  • [43] An HIV-infected patient with associated, lethal rhinopharyngeal actinomycosis and a rapidly progressing local adenocarcinoma
    Manfredi, Roberto
    Sabbatani, Sergio
    Fulgaro, Ciro
    RETROVIROLOGY, 2010, 7 : 26 - 27
  • [44] GENETIC IMPLICATIONS OF INTERACTION OF 2 TYPES OF BETA-THALASSEMIA GENES IN A PATIENT WITH THALASSEMIA MAJOR
    RUSSO, G
    MOLLICA, F
    PAVONE, L
    MUSUMECI, S
    BAGLIONI, C
    BLOOD, 1973, 42 (05) : 763 - 769
  • [45] Systemic lupus erythematosus in a patient with beta-thalassemia major
    Voulgari, PV
    Karali, A
    Alymara, V
    Chaidos, A
    Bourantas, KL
    Drosos, AA
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2005, 23 (02) : 278 - 278
  • [46] ARDS in a patient with homozygous beta-thalassemia due to yersiniosis
    P. Mavrommati
    V. Ladis
    E. Lagona
    M. Giannaki
    A. Raftopoulou
    T. Hatzis
    Intensive Care Medicine, 1999, 25 : 226 - 229
  • [47] HEPATIC FOCAL EXTRAMEDULLARY HEMATOPOIESIS IN PATIENT WITH INTERMEDIATE BETA THALASSEMIA
    Galan Vega, J.
    Alvarez Juarez Miguel, A.
    Herrera, F.
    Lopez Prieto, C.
    Escolano Escobar, C.
    Carmona Zabala, I
    del Monteserin Monteserin, M. C.
    Ona Compan, F.
    Benito Parra, L.
    HAEMATOLOGICA, 2019, 104 : 418 - 419
  • [48] CHARACTERIZATION OF THE BETA+-THALASSEMIA MUTATION IN A HOMOZYGOUS YUGOSLAVIAN PATIENT
    GILMAN, JG
    HUISMAN, THJ
    STOJANOVSKI, N
    EFREMOV, GD
    HEMOGLOBIN, 1984, 8 (05) : 529 - 533
  • [49] Cardiac Myxoma Showing Extramedullary Hematopoiesis in a Patient with Beta Thalassemia
    Joukhadar, Rene
    De Las Casas, Luis E.
    Lalude, Omosalewa
    Gough, David
    SOUTHERN MEDICAL JOURNAL, 2009, 102 (07) : 769 - 771
  • [50] THROMBOEMBOLIC COMPLICATIONS IN AN ASPLENIC HBE-BETA-THALASSEMIA PATIENT
    VANTEUNENBROEK, A
    WIJBURG, FA
    TENCATE, JW
    VANDENBERG, W
    WEENING, RS
    NETHERLANDS JOURNAL OF MEDICINE, 1989, 35 (3-4): : 123 - 127
12345