Rapidly progressing bilateral cataracts in a patient with beta thalassemia and pellagra

被引：8
|
作者：
Athanasiadis, Ioannis
Konstantinidis, Aristeidis
Kyprianou, Ioannis
Robinson, Rosemary
Moschou, Vaia
Kouzi-Koliakos, Kokkona
机构：
[1] Coventry & Warwickshire Univ Hosp NHS Trust, Dept Ophthalmol, Walsgrave Hosp, Coventry, W Midlands, England
[2] Aristotle Univ Thessaloniki, AHEPA Univ Hosp, Thessaloniki, Greece
来源：
JOURNAL OF CATARACT AND REFRACTIVE SURGERY | 2007年 / 33卷 / 09期
关键词：
D O I：
10.1016/j.jcrs.2007.05.011
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Soon after the diagnosis of pellagra in a 20-year-old patient with beta thalassemia, bilateral intumescent cataracts rapidly developed. We believe the patient's crystalline lenses were at an increased oxidative state due to iron overload from the thalassemia. Depletion of the lens epithelial cells of an important antioxidative agent (glutathione) as a result of niacin (vitamin B3) deficiency due to pellagra reduced the antioxidative capacity of the lenses. The oxidative damage led to rapid development of cataracts.
引用
收藏
页码：1659 / 1661
页数：3
相关论文
共 50 条
  • [31] Primary Cutaneous Mucormycosis in a Beta-Thalassemia Patient
    Mozhdeh Sepaskhah
    Iman Moezzi
    Mohammad Ali Davarpanah
    Fatemeh Sari Aslani
    Indian Journal of Hematology and Blood Transfusion, 2018, 34 : 776 - 777
  • [32] Pulmonary hypertension in a patient with beta-thalassemia major
    Mérault, JM
    Escamilla, R
    Degano, B
    Guittard, J
    Hermant, C
    Krempf, M
    REVUE DES MALADIES RESPIRATOIRES, 2000, 17 (03) : 689 - 691
  • [33] Extramedullary Hematopoiesis in a Patient with Beta Thalassemia: A Rare Case
    Alqahtani, Mohammed Saad
    INTERNATIONAL JOURNAL OF BIOMEDICINE, 2024, 14 (02) : 345 - 347
  • [34] ANAESTHETIC MANAGEMENT OF A PATIENT WITH SICKLE beta(+) THALASSEMIA WITH CHOLELITHIASIS
    Murthy, M.
    Murthy, R.
    Nigam, R.
    Kosam, D.
    JOURNAL OF EVOLUTION OF MEDICAL AND DENTAL SCIENCES-JEMDS, 2014, 3 (21): : 5652 - 5657
  • [35] Rapidly vanishing lung pseudotumor in a patient with acute bilateral bronchopneumonia
    Lazovic, Biljana
    Stajic, Zoran
    Putnikovic, Biljana
    VOJNOSANITETSKI PREGLED, 2013, 70 (09) : 878 - 880
  • [36] RAPIDLY PROGRESSIVE SEPSIS SECONDARY TO BILATERAL EMPYEMA IN AN IMMUNOCOMPETENT PATIENT
    Dwumah-Agyen, Matthew
    Shrestha, Anish
    Mensah, Boniface
    Yeboah-Kordieh, Yvette
    Wolff, Marcos
    Evans, Jennifer
    CRITICAL CARE MEDICINE, 2025, 53 (01)
  • [37] Dramatic improvement of rapidly progressing acute renal failure and severe hypertension after bilateral renal artery stenting
    Shinozaki N.
    Hoshino K.
    Nishimura R.
    Tamura K.
    Cardiovascular Intervention and Therapeutics, 2011, 26 (1) : 74 - 78
  • [38] Early and rapidly progressing respiratory failure in a patient with amyotrophic lateral sclerosis: when FVC% is misleading
    Grazia Crescimanno
    Marcello Romano
    Rossella Spataro
    Vincenzo La Bella
    Oreste Marrone
    Neurological Sciences, 2019, 40 : 421 - 422
  • [39] Early and rapidly progressing respiratory failure in a patient with amyotrophic lateral sclerosis: when FVC% is misleading
    Crescimanno, Grazia
    Romano, Marcello
    Spataro, Rossella
    La Bella, Vincenzo
    Marrone, Oreste
    NEUROLOGICAL SCIENCES, 2019, 40 (02) : 421 - 422
  • [40] RAPIDLY PROGRESSING, MASSIVE MITRAL ANNULAR CALCIFICATION - OCCURRENCE IN A PATIENT WITH CHRONIC-RENAL-FAILURE
    DEPACE, NL
    ROHRER, AH
    KOTLER, MN
    BREZIN, JH
    PARRY, WR
    ARCHIVES OF INTERNAL MEDICINE, 1981, 141 (12) : 1663 - 1665
12345