Involvement of phenotypes and serum levels of haptoglobin in the outcome of in vitro fertilization and embryo transfer

被引:3
|
作者
Ueda, K [1 ]
Yamamasu, S [1 ]
Nakamura, Y [1 ]
Honda, K [1 ]
Ozaki, K [1 ]
Fujino, Y [1 ]
Ishiko, O [1 ]
Ogita, S [1 ]
机构
[1] Osaka City Univ, Sch Med, Dept Obstet & Gynecol, Osaka 5458585, Japan
关键词
haptoglobin; phenotype infertility; in vitro fertilization and embryo transfer;
D O I
10.1159/000058053
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Haptoglobin (Hp) possesses many functions in the immune system and angiogenesis as well as scavenging released hemoglobin, and thus it is speculated that Hp may also play a critical role in the reproductive process, To investigate the possible involvement of Hp in the outcome of in vitro fertilization and embryo transfer (IVF-ET), the serum Hp of 50 patients who underwent IVF-ET was analyzed by the Western blot method. The results showed a higher pregnancy rate in the patients with the Hp2-2 phenotype (38%) than in those with the Hp2-1 phenotype (16%) (p = 0.08), and the serum alpha2 subunit levels in the patients who achieved pregnancy within four attempts at IVF-ET were higher than in the others (p < 0.05), The results of this study suggest that Hp is involved in the outcome of IVF-ET, Copyright (C) 2001 S. Karger AG. Basel.
引用
收藏
页码:219 / 222
页数:4
相关论文
共 50 条
  • [41] Anticardiolipin antibody levels in women undergoing first in vitro fertilization/embryo transfer
    Caccavo, D.
    Pellegrino, N. M.
    Lorusso, F.
    Capotorto, M.
    Vacca, M.
    Vimercati, A.
    Depalo, R.
    HUMAN REPRODUCTION, 2007, 22 (09) : 2494 - 2500
  • [42] Relationship between serum antisperm antibodies and anticardiolipin antibodies and clinical pregnancy outcome in an in vitro fertilization and embryo transfer program
    田秀珠
    张丽珠
    吴燕
    杨池荪
    刘平
    ChineseMedicalJournal, 1999, (01)
  • [43] Relationship between serum antisperm antibodies and anticardiolipin antibodies and clinical pregnancy outcome in an in vitro fertilization and embryo transfer program
    田秀珠
    张丽珠
    吴燕
    杨池荪
    刘平
    中华医学杂志(英文版), 1999, (01) : 35 - 37
  • [44] CA-125 serum levels and pregnancy outcome in in vitro fertilization
    Fish, KE
    Phipps, M
    Trimarchi, J
    Weitzen, S
    Blazar, AS
    FERTILITY AND STERILITY, 2004, 82 (06) : 1705 - 1707
  • [45] Relationship between serum antisperm antibodies and anticardiolipin antibodies and clinical pregnancy outcome in an in vitro fertilization and embryo transfer program
    Tian, XH
    Zhang, LH
    Wu, Y
    Yang, CS
    Liu, P
    CHINESE MEDICAL JOURNAL, 1999, 112 (01) : 34 - 36
  • [46] Impact of hypnosis during embryo transfer on the outcome of in vitro fertilization-embryo transfer: a case-control study
    Levitas, Eliahu
    Parmet, Aldo
    Lunenfeld, Eitan
    Bentov, Yacov
    Burstein, Eliezer
    Friger, Michael
    Potashnik, Gad
    FERTILITY AND STERILITY, 2006, 85 (05) : 1404 - 1408
  • [47] Exogenous gonadotropin stimulation is associated with increases in serum androgen levels in in-vitro fertilization-embryo transfer cycles
    Martin, KA
    Hornstein, MD
    Taylor, AE
    Hall, JE
    Barbieri, RL
    FERTILITY AND STERILITY, 1997, 68 (06) : 1011 - 1016
  • [48] Seasonal Influences on In Vitro Fertilization and Embryo Transfer
    Monika Weigert
    Wilfried Feichtinger
    Sandor Kulin
    Steven G. Kaali
    Petra Dorau
    Peter Bauer
    Journal of Assisted Reproduction and Genetics, 2001, 18 : 598 - 602
  • [50] FOLLICULAR FACTORS, SERUM ESTRADIOL, AND OUTCOME OF PREGNANCY FOLLOWING INVITRO FERTILIZATION AND EMBRYO TRANSFER
    LEWINTHAL, D
    MAHADEVAN, M
    PATTINSON, HA
    TAYLOR, PJ
    PERSAUD, D
    FERTILITY AND STERILITY, 1987, 48 (05) : 840 - 842