haptoglobin;
phenotype infertility;
in vitro fertilization and embryo transfer;
D O I:
10.1159/000058053
中图分类号:
R71 [妇产科学];
学科分类号:
100211 ;
摘要:
Haptoglobin (Hp) possesses many functions in the immune system and angiogenesis as well as scavenging released hemoglobin, and thus it is speculated that Hp may also play a critical role in the reproductive process, To investigate the possible involvement of Hp in the outcome of in vitro fertilization and embryo transfer (IVF-ET), the serum Hp of 50 patients who underwent IVF-ET was analyzed by the Western blot method. The results showed a higher pregnancy rate in the patients with the Hp2-2 phenotype (38%) than in those with the Hp2-1 phenotype (16%) (p = 0.08), and the serum alpha2 subunit levels in the patients who achieved pregnancy within four attempts at IVF-ET were higher than in the others (p < 0.05), The results of this study suggest that Hp is involved in the outcome of IVF-ET, Copyright (C) 2001 S. Karger AG. Basel.
机构:
Beijing Med Univ, Clin Med Sch 3, Dept Obstet & Gynecol, Beijing 100083, Peoples R ChinaBeijing Med Univ, Clin Med Sch 3, Dept Obstet & Gynecol, Beijing 100083, Peoples R China
Tian, XH
Zhang, LH
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机构:
Beijing Med Univ, Clin Med Sch 3, Dept Obstet & Gynecol, Beijing 100083, Peoples R ChinaBeijing Med Univ, Clin Med Sch 3, Dept Obstet & Gynecol, Beijing 100083, Peoples R China
Zhang, LH
Wu, Y
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机构:
Beijing Med Univ, Clin Med Sch 3, Dept Obstet & Gynecol, Beijing 100083, Peoples R ChinaBeijing Med Univ, Clin Med Sch 3, Dept Obstet & Gynecol, Beijing 100083, Peoples R China
Wu, Y
Yang, CS
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Beijing Med Univ, Clin Med Sch 3, Dept Obstet & Gynecol, Beijing 100083, Peoples R ChinaBeijing Med Univ, Clin Med Sch 3, Dept Obstet & Gynecol, Beijing 100083, Peoples R China
Yang, CS
Liu, P
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机构:
Beijing Med Univ, Clin Med Sch 3, Dept Obstet & Gynecol, Beijing 100083, Peoples R ChinaBeijing Med Univ, Clin Med Sch 3, Dept Obstet & Gynecol, Beijing 100083, Peoples R China