Involvement of phenotypes and serum levels of haptoglobin in the outcome of in vitro fertilization and embryo transfer

被引：3

作者：

Ueda, K ^{[1
]}

Yamamasu, S ^{[1
]}

Nakamura, Y ^{[1
]}

Honda, K ^{[1
]}

Ozaki, K ^{[1
]}

Fujino, Y ^{[1
]}

Ishiko, O ^{[1
]}

Ogita, S ^{[1
]}

机构：

[1] Osaka City Univ, Sch Med, Dept Obstet & Gynecol, Osaka 5458585, Japan

来源：

GYNECOLOGIC AND OBSTETRIC INVESTIGATION | 2001年 / 51卷 / 04期

关键词：

haptoglobin; phenotype infertility; in vitro fertilization and embryo transfer;

D O I：

10.1159/000058053

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Haptoglobin (Hp) possesses many functions in the immune system and angiogenesis as well as scavenging released hemoglobin, and thus it is speculated that Hp may also play a critical role in the reproductive process, To investigate the possible involvement of Hp in the outcome of in vitro fertilization and embryo transfer (IVF-ET), the serum Hp of 50 patients who underwent IVF-ET was analyzed by the Western blot method. The results showed a higher pregnancy rate in the patients with the Hp2-2 phenotype (38%) than in those with the Hp2-1 phenotype (16%) (p = 0.08), and the serum alpha2 subunit levels in the patients who achieved pregnancy within four attempts at IVF-ET were higher than in the others (p < 0.05), The results of this study suggest that Hp is involved in the outcome of IVF-ET, Copyright (C) 2001 S. Karger AG. Basel.

引用

页码：219 / 222

页数：4

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