Beyond Fat Mass: Exploring the Role of Adipokines in Rheumatic Diseases

被引：55

作者：

Scotece, Morena ^{[1
]}

Conde, Javier ^{[1
]}

Gomez, Rodolfo ^{[2
]}

Lopez, Veronica ^{[1
]}

Lago, Francisca ^{[3
]}

Jesus Gomez-Reino, Juan ^{[1
]}

Gualillo, Oreste ^{[1
]}

机构：

[1] Santiago Univ Clin Hosp, Inst Med Res IDIS, SERGAS,Res Lab 9, Lab Neuroendocrine Interact Rheumatol & Inflammat, Santiago De Compostela 15706, Spain

[2] Fdn Jimenez Diaz, Div Reumatol, E-28040 Madrid, Spain

[3] Santiago Univ Clin Hosp, Inst Med Res IDIS, SERGAS, Mol & Cellular Cardiol Lab,Res Lab 7, Santiago De Compostela 15706, Spain

来源：

THESCIENTIFICWORLDJOURNAL | 2011年 / 11卷

关键词：

white adipose tissue (WAT); adipokines; cytokines; rheumatic diseases; immune response; immune tolerance; metabolism; energetic homeostasis; GELATINASE-ASSOCIATED LIPOCALIN; SYSTEMIC-LUPUS-ERYTHEMATOSUS; SYNTHASE TYPE-II; HUMAN ARTICULAR CHONDROCYTES; VISCERAL ADIPOSE-TISSUE; ACUTE-PHASE REACTANTS; KNEE OSTEOARTHRITIS; METABOLIC SYNDROME; SYNOVIAL-FLUID; TNF-ALPHA;

D O I：

10.1100/2011/290142

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The cloning of leptin in 1994 by Zhang et al. introduced a novel concept about white adipose tissue (WAT) as a very dynamic organ that releases a plethora of immune and inflammatory mediators, such as adipokines and cytokines, which are involved in multiple diseases. Actually, adipokines exert potent modulatory actions on target tissues involved in rheumatic diseases including cartilage, synovial, bone and immune cells. The goal of this paper is to elucidate the recent findings concerning the involvement of adipokines in rheumatic diseases, such as rheumatoid arthritis (RA), osteoarthritis (OA), and systemic lupus erythematosus (SLE).

引用

页码：1932 / 1947

页数：16

共 50 条

[11] Inflammation, adipokines, rheumatic diseases: Immunology approach
Tilg, H.
ANNALS OF THE RHEUMATIC DISEASES, 2007, 66 : 9 - 9
[12] METABOLIC SYNDROME, INFLAMMATION AND ATHEROSCLEROSIS - THE ROLE OF ADIPOKINES IN HEALTH AND IN SYSTEMIC INFLAMMATORY RHEUMATIC DISEASES
Santos, Maria Jose
Fonseca, Joao Eurico
ACTA REUMATOLOGICA PORTUGUESA, 2009, 34 (04): : 590 - 598
[13] Adipokines in young survivors of childhood acute lymphocytic leukemia revisited: beyond fat mass
Siviero-Miachon, Adriana Aparecida
Spinola-Castro, Angela Maria
Andreoni, Solange
de Martino Lee, Maria Lucia
Calixto, Antonio R.
Geloneze, Bruno
Guerra-Junior, Gil
ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 2020, 25 (03) : 174 - 181
[14] The Influence of Adipokines on Radiographic Damage in Inflammatory Rheumatic Diseases
Toussirot, Eric
BIOMEDICINES, 2023, 11 (02)
[15] Beyond Seasoning-The Role of Herbs and Spices in Rheumatic Diseases
Charneca, Sofia
Hernando, Ana
Costa-Reis, Patricia
Guerreiro, Catarina Sousa
NUTRIENTS, 2023, 15 (12)
[16] A new perspective: Fat tissue and adipokines in rheumatic heart valves
Xie, Ting
Wu, Danna
Zhang, Jie
Qiao, Ping
Chen, Xuan
Liu, Debin
Xiang, Mei
Li, Haitao
Cai, Xingjiu
Lin, Zhichuan
Yang, Wenkai
Chen, Xinzhong
Chen, Hao
Liu, Cong
JOURNAL OF CARDIAC SURGERY, 2022, 37 (12) : 4991 - 4998
[17] Role of fat and adipokines in intestinal inflammation
Kredel, Leal
Batra, Arvind
Siegmund, Britta
CURRENT OPINION IN GASTROENTEROLOGY, 2014, 30 (06) : 559 - 565
[18] Adipokines: Some players of inflammation in inflammatory rheumatic diseases and systemic autoimmune diseases?
Toussirot, Eric
PRESSE MEDICALE, 2013, 42 (01): : 13 - 18
[19] Adipokines and Chronic Rheumatic Diseases: from Inflammation to Bone Involvement
Cici, Daniela
Corrado, Addolorata
Rotondo, Cinzia
Colia, Ripalta
Cantatore, Francesco Paolo
CLINICAL REVIEWS IN BONE AND MINERAL METABOLISM, 2020, 18 (04): : 58 - 71
[20] Adipokines and Chronic Rheumatic Diseases: from Inflammation to Bone Involvement
Daniela Cici
Addolorata Corrado
Cinzia Rotondo
Ripalta Colia
Francesco Paolo Cantatore
Clinical Reviews in Bone and Mineral Metabolism, 2020, 18 : 58 - 71

← 1 2 3 4 5 →