Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors

被引：1
|
作者：
Marusiak, A. A. [1 ]
Edwards, Z. C. [1 ]
Hugo, W. [2 ]
Trotter, E. W. [1 ]
Girotti, M. R. [3 ]
Stephenson, N. L. [1 ]
Kong, X. [2 ]
Gartside, M. G. [4 ]
Fawdar, S. [1 ]
Hudson, A. [1 ]
Breitwieser, W. [3 ]
Hayward, N. K. [4 ]
Marais, R. [3 ]
Lo, R. S. [2 ]
Brognard, J. [1 ]
机构：
[1] Canc Res UK Manchester Inst, Signalling Networks Canc, Manchester, Lancs, England
[2] Jonsson Comprehens Canc Ctr, Div Dermatol, Los Angeles, CA 90034 USA
[3] Canc Res UK Manchester Inst, Manchester, Lancs, England
[4] QIMR Berghofer Med Res Inst, Brisbane, Qld, Australia
来源：
EUROPEAN JOURNAL OF CANCER | 2014年 / 50卷
关键词：
D O I：
10.1016/S0959-8049(14)70202-3
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
76
引用
收藏
页码：29 / 30
页数：2
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