Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors

被引：1

作者：

Marusiak, A. A. ^{[1
]}

Edwards, Z. C. ^{[1
]}

Hugo, W. ^{[2
]}

Trotter, E. W. ^{[1
]}

Girotti, M. R. ^{[3
]}

Stephenson, N. L. ^{[1
]}

Kong, X. ^{[2
]}

Gartside, M. G. ^{[4
]}

Fawdar, S. ^{[1
]}

Hudson, A. ^{[1
]}

Breitwieser, W. ^{[3
]}

Hayward, N. K. ^{[4
]}

Marais, R. ^{[3
]}

Lo, R. S. ^{[2
]}

Brognard, J. ^{[1
]}

机构：

[1] Canc Res UK Manchester Inst, Signalling Networks Canc, Manchester, Lancs, England

[2] Jonsson Comprehens Canc Ctr, Div Dermatol, Los Angeles, CA 90034 USA

[3] Canc Res UK Manchester Inst, Manchester, Lancs, England

[4] QIMR Berghofer Med Res Inst, Brisbane, Qld, Australia

来源：

EUROPEAN JOURNAL OF CANCER | 2014年 / 50卷

关键词：

D O I：

10.1016/S0959-8049(14)70202-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：29 / 30

页数：2

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