Ultrastructure of the pineal gland after γ-irradiation under conditions of inhibition of adrenocortical function

被引：0
|
作者：
Popuchiev, VV [1 ]
Yakovleva, ND
Konoplyannikov, AG
Kvetnoi, IM
Kita, K
Kita, I
机构：
[1] Russian Acad Med Sci, Res Ctr, Obninsk, Russia
[2] Russian Acad Med Sci, St Petersburg Inst Bioregulat & Gerontol, Norwestern Div, Moscow 109801, Russia
[3] Inst Ind Organ Chem, Warsaw, Poland
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2003年 / 135卷 / 06期
关键词：
pineal gland; gamma-irradiation; ultrastructure; metopirone;
D O I：
10.1023/A:1025402007545
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Electron microscopy showed that whole-body gamma-irradiation in sublethal doses led to the appearance of injuries in pinealocytes, glial cells, and vessels of the pineal gland in rats. Limitation of the nonspecific effect of gamma-irradiation via inhibition of adrenocortical function with metopirone in physiological doses reduced the radiation-induced ultrastructural damage to the pineal gland.
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页码：603 / 607
页数：5
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