Ultrastructure of the pineal gland after γ-irradiation under conditions of inhibition of adrenocortical function

被引：0

作者：

Popuchiev, VV ^{[1
]}

Yakovleva, ND

Konoplyannikov, AG

Kvetnoi, IM

Kita, K

Kita, I

机构：

[1] Russian Acad Med Sci, Res Ctr, Obninsk, Russia

[2] Russian Acad Med Sci, St Petersburg Inst Bioregulat & Gerontol, Norwestern Div, Moscow 109801, Russia

[3] Inst Ind Organ Chem, Warsaw, Poland

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2003年 / 135卷 / 06期

关键词：

pineal gland; gamma-irradiation; ultrastructure; metopirone;

D O I：

10.1023/A:1025402007545

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Electron microscopy showed that whole-body gamma-irradiation in sublethal doses led to the appearance of injuries in pinealocytes, glial cells, and vessels of the pineal gland in rats. Limitation of the nonspecific effect of gamma-irradiation via inhibition of adrenocortical function with metopirone in physiological doses reduced the radiation-induced ultrastructural damage to the pineal gland.

引用

页码：603 / 607

页数：5

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