Computational cancer biology: education is a natural key to many locks

被引:5
|
作者
Emmert-Streib, Frank [1 ]
Zhang, Shu-Dong [2 ]
Hamilton, Peter [2 ]
机构
[1] Queens Univ Belfast, Fac Med Hlth & Life Sci, Sch Med Dent & Biomed Sci, Ctr Canc Res & Cell Biol,Computat Biol & Machine, Belfast, Antrim, North Ireland
[2] Queens Univ Belfast, Fac Med Hlth & Life Sci, Sch Med Dent & Biomed Sci, Ctr Canc Res & Cell Biol, Belfast, Antrim, North Ireland
关键词
Cancer; Computational biology; Genomics data; Computational oncology; Computational genomics; Statistical genomics; Systems medicine; EXPRESSION; CLASSIFICATION; CARCINOMAS;
D O I
10.1186/s12885-014-1002-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Oncology is a field that profits tremendously from the genomic data generated by high-throughput technologies, including next-generation sequencing. However, in order to exploit, integrate, visualize and interpret such high-dimensional data efficiently, non-trivial computational and statistical analysis methods are required that need to be developed in a problem-directed manner. Discussion: For this reason, computational cancer biology aims to fill this gap. Unfortunately, computational cancer biology is not yet fully recognized as a coequal field in oncology, leading to a delay in its maturation and, as an immediate consequence, an under-exploration of high-throughput data for translational research. Summary: Here we argue that this imbalance, favoring 'wet lab-based activities', will be naturally rectified over time, if the next generation of scientists receives an academic education that provides a fair and competent introduction to computational biology and its manifold capabilities. Furthermore, we discuss a number of local educational provisions that can be implemented on university level to help in facilitating the process of harmonization.
引用
收藏
页数:6
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