HIV-2 and T cell recognition

被引：26
|
作者：
Whittle, HC
Ariyoshi, K
Rowland-Jones, S
机构：
[1] MRC Labs, Banjul, Gambia
[2] Natl Inst Infect Dis, Ctr AIDS Res, Grp 2, Tokyo 2080011, Japan
[3] John Radcliffe Hosp, Inst Mol Med, Mol Immunol Grp, Oxford OX3 9DU, England
来源：
CURRENT OPINION IN IMMUNOLOGY | 1998年 / 10卷 / 04期
关键词：
D O I：
10.1016/S0952-7915(98)80108-8
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
HIV-2 is less pathogenic and less transmissible than HIV-1. Recent research in relation to deletions in the HIV nef gene and to immune cross-reactions between infections by HIV-2, HIV-1 and simian immunodeficiency virus suggests that T cell recognition and the control of viral replication may be more efficient in HIV-2 infection than in HIV-1 infection. These insights may be crucial to the design of effective vaccines.
引用
收藏
页码：382 / 387
页数：6
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