HIV-2 and T cell recognition

被引：26

作者：

Whittle, HC

Ariyoshi, K

Rowland-Jones, S

机构：

[1] MRC Labs, Banjul, Gambia

[2] Natl Inst Infect Dis, Ctr AIDS Res, Grp 2, Tokyo 2080011, Japan

[3] John Radcliffe Hosp, Inst Mol Med, Mol Immunol Grp, Oxford OX3 9DU, England

来源：

CURRENT OPINION IN IMMUNOLOGY | 1998年 / 10卷 / 04期

关键词：

D O I：

10.1016/S0952-7915(98)80108-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

HIV-2 is less pathogenic and less transmissible than HIV-1. Recent research in relation to deletions in the HIV nef gene and to immune cross-reactions between infections by HIV-2, HIV-1 and simian immunodeficiency virus suggests that T cell recognition and the control of viral replication may be more efficient in HIV-2 infection than in HIV-1 infection. These insights may be crucial to the design of effective vaccines.

引用

页码：382 / 387

页数：6

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