Hepatic arterial floxuridine as second-line treatment for systemic fluorouracil-resistant colorectal liver metastases

被引：24
|
作者：
Fordy, C [1 ]
Glover, C [1 ]
Davies, MM [1 ]
Allen-Mersh, TG [1 ]
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Chelsea & Westminster Hosp, Sch Med, Dept Gastrointestinal Surg, London, England
来源：
BRITISH JOURNAL OF CANCER | 1998年 / 78卷 / 08期
关键词：
colorectal liver metastases; chemotherapy; fluorouracil resistance; hepatic arterial floxuridine;
D O I：
10.1038/bjc.1998.627
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Hepatic arterial floxuridine (HAI) in 35 patients with systemic fluorouracil/folinic acid-resistant colorectal liver metastases achieved a 14% partial response and 26% disease stabilization rate, with a median response duration of 7 months from onset of HAI.
引用
收藏
页码：1058 / 1060
页数：3
相关论文
共 50 条
  • [21] Regional treatment with floxuridine infused by non surgically implanted arterial port as second line therapy for colorectal liver metastasis
    Zanon, C
    Grosso, M
    Miraglia, S
    Clara, R
    Chiappino, I
    Evangelisti, L
    Martinotti, R
    Mussa, A
    Alabiso, O
    ANNALS OF ONCOLOGY, 1998, 9 : 162 - 162
  • [22] Selective Intra-arterial Chemotherapy with Floxuridine as Second- or Third-Line Approach in Patients with Unresectable Colorectal Liver Metastases
    Panagiotis Samaras
    S. Breitenstein
    S. R. Haile
    F. Stenner-Liewen
    S. Heinrich
    J. Feilchenfeldt
    C. Renner
    A. Knuth
    B. C. Pestalozzi
    P. A. Clavien
    Annals of Surgical Oncology, 2011, 18 : 1924 - 1931
  • [23] Weekly hepatic arterial infusion of 5-fluorouracil and subsequent systemic chemotherapy for liver metastases from colorectal cancer
    Hosokawa, A
    Yamada, Y
    Shimada, Y
    Muro, K
    Matsumura, Y
    Fujita, S
    Akasu, T
    Moriya, Y
    Shirao, K
    JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 2003, 33 (03) : 132 - 135
  • [24] Phase I study of hepatic arterial infusion of floxuridine and dexamethasone with systemic irinotecan for unresectable hepatic metastases from colorectal cancer
    Kemeny, N
    Gonen, M
    Sullivan, D
    Schwartz, L
    Benedetti, F
    Saltz, L
    Stockman, J
    Fong, Y
    Jarnagin, W
    Bertino, J
    Tong, W
    Paty, P
    JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (10) : 2687 - 2695
  • [25] Is Resection of Colorectal Liver Metastases After a Second-Line Chemotherapy Regimen Justified?
    Brouquet, Antoine
    Overman, Michael J.
    Kopetz, Scott
    Maru, Dipen M.
    Loyer, Evelyne M.
    Andreou, Andreas
    Cooper, Amanda
    Curley, Steven A.
    Garrett, Christopher R.
    Abdalla, Eddie K.
    Vauthey, Jean-Nicolas
    CANCER, 2011, 117 (19) : 4484 - 4492
  • [26] Is there a new drug beyond floxuridine for intra-arterial hepatic chemotherapy in liver metastases from colorectal cancer?
    Fiorentini, G
    Rossi, S
    Bernardeschi, P
    Cantore, M
    Guadagni, S
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (09) : 2105 - 2105
  • [27] Hepatic Arterial Infusion for Unresectable Colorectal Liver Metastases Combined or Not with Systemic Chemotherapy
    Pilati, Pierluigi
    Mammano, Enzo
    Mocellin, Simone
    Tessari, Emanuela
    Lise, Mario
    Nitti, Donato
    ANTICANCER RESEARCH, 2009, 29 (10) : 4139 - 4144
  • [28] Irinotecan as second-line treatment for unresectable liver metastases of colon cancer
    Nomura H.
    Takahashi Y.
    Mai M.
    International Journal of Clinical Oncology, 1998, 3 (2) : 117 - 120
  • [29] Hepatic arterial chemotherapy for colorectal liver metastases
    Mathur, P
    Allen-Mersh, TG
    HEPATO-GASTROENTEROLOGY, 2001, 48 (38) : 317 - 319
  • [30] Conventional transarterial chemoembolization combined with systemic therapy versus systemic therapy alone as second-line treatment for unresectable colorectal liver metastases: randomized clinical trial
    Liu, Y.
    Chang, W.
    Zhou, B.
    Wei, Y.
    Tang, W.
    Liang, F.
    Chen, Y.
    Yan, Z.
    Lv, M.
    Ren, L.
    Xu, J.
    BRITISH JOURNAL OF SURGERY, 2021, 108 (04) : 373 - 379
12345