Hepatic arterial floxuridine as second-line treatment for systemic fluorouracil-resistant colorectal liver metastases

被引：24
|
作者：
Fordy, C [1 ]
Glover, C [1 ]
Davies, MM [1 ]
Allen-Mersh, TG [1 ]
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Chelsea & Westminster Hosp, Sch Med, Dept Gastrointestinal Surg, London, England
来源：
BRITISH JOURNAL OF CANCER | 1998年 / 78卷 / 08期
关键词：
colorectal liver metastases; chemotherapy; fluorouracil resistance; hepatic arterial floxuridine;
D O I：
10.1038/bjc.1998.627
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Hepatic arterial floxuridine (HAI) in 35 patients with systemic fluorouracil/folinic acid-resistant colorectal liver metastases achieved a 14% partial response and 26% disease stabilization rate, with a median response duration of 7 months from onset of HAI.
引用
收藏
页码：1058 / 1060
页数：3
相关论文
共 50 条
  • [1] Hepatic arterial floxuridine as second-line treatment for systemic fluorouracil-resistant colorectal liver metastases
    C Fordy
    C Glover
    MM Davies
    TG Allen-Mersh
    British Journal of Cancer, 1998, 78 : 1058 - 1060
  • [2] Oxaliplatin in the second-line treatment of fluorouracil-resistant colorectal cancer.
    Wilson, G
    Papamichael, P
    Dent, JT
    Richards, F
    Slevin, ML
    Seymour, MT
    BRITISH JOURNAL OF CANCER, 1998, 78 : 29 - 29
  • [3] Hepatic arterial infusion (HAI) of cisplatin and systemic fluorouracil in the treatment of unresectable colorectal liver metastases
    Mancini, R
    Tedesco, M
    Garufi, C
    Filippini, A
    Arcieri, S
    Caterino, M
    Pizzi, G
    Cortesi, E
    Spila, A
    Sperduti, I
    Cosimelli, M
    ANTICANCER RESEARCH, 2003, 23 (2C) : 1837 - 1841
  • [4] Systemic exposure of floxuridine after hepatic arterial infusion pump chemotherapy with floxuridine in patients with resected colorectal liver metastases
    IJzerman, Nikki S.
    Filipe, Wills F.
    de Bruijn, Peter
    Buisman, Florian E.
    van Doorn, Leni
    Doornebosch, Pascal G.
    Holster, Jessica J.
    Grootscholten, Cecile
    Gruenhagen, Dirk J.
    van Bommel, Christian P. E.
    Homs, Marjolein Y. V.
    Kok, Niels F. M.
    Verhoef, Cornelis
    Koerkamp, Bas Groot
    Kuhlmann, Koert F. D.
    Mathijssen, Ron H. J.
    Koolen, Stijn L. W.
    BIOMEDICINE & PHARMACOTHERAPY, 2023, 162
  • [5] Alternating floxuridine and 5-fluorouracil hepatic arterial chemotherapy for colorectal liver metastases minimizes biliary toxicity
    Davidson, BS
    Izzo, F
    Chase, JL
    DuBrow, RA
    Patt, Y
    Hohn, DC
    Curley, SA
    AMERICAN JOURNAL OF SURGERY, 1996, 172 (03): : 244 - 247
  • [6] Hepatic Arterial Infusion with Irinotecan, Oxaliplatin, and Floxuridine plus Systemic Chemotherapy as First-Line Treatment of Unresectable Liver Metastases from Colorectal Cancer
    Chen, Yi
    Wang, Xiaolin
    Yan, Zhiping
    Wang, Jianhua
    Luo, Jianjun
    Liu, Qingxin
    ONKOLOGIE, 2012, 35 (09): : 480 - 484
  • [7] Transarterial Radioembolization for Colorectal Cancer Liver Metastases Is Effective as a Second-Line Treatment
    Chandra, Vishnu
    RADIOLOGY-IMAGING CANCER, 2023, 5 (01): : e239003
  • [8] HEPATIC ARTERIAL FLOXURIDINE AND LEUCOVORIN FOR UNRESECTABLE LIVER METASTASES FROM COLORECTAL-CARCINOMA
    KEMENY, N
    SEITER, K
    CONTI, JA
    COHEN, A
    BERTINO, JR
    SIGURDSON, ER
    BOTET, J
    CHAPMAN, D
    MAZUMDAR, M
    BUDD, AJ
    CANCER, 1994, 73 (04) : 1134 - 1142
  • [9] ALTERNATING HEPATIC INTRAARTERIAL FLOXURIDINE AND FLUOROURACIL - A LESS TOXIC REGIMEN FOR TREATMENT OF LIVER METASTASES FROM COLORECTAL-CANCER
    STAGG, RJ
    VENOOK, AP
    CHASE, JL
    LEWIS, BJ
    WARREN, RS
    ROH, M
    MULVIHILL, SJ
    GROBMAN, BJ
    RAYNER, AA
    HOHN, DC
    JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1991, 83 (06) : 423 - 428
  • [10] INTRAARTERIAL FLOXURIDINE VS SYSTEMIC FLUOROURACIL FOR HEPATIC METASTASES FROM COLORECTAL-CANCER - A RANDOMIZED TRIAL
    MARTIN, JK
    OCONNELL, MJ
    WIEAND, HS
    FITZGIBBONS, RJ
    MAILLIARD, JA
    RUBIN, J
    NAGORNEY, DM
    TSCHETTER, LK
    KROOK, JE
    ARCHIVES OF SURGERY, 1990, 125 (08) : 1022 - 1027
12345