Palladium-Catalyzed Direct C-H Bond Alkynylations of Heteroarenes Using gem-Dichloroalkenes

被引：49
|
作者：
Ackermann, Lutz [1 ]
Kornhaass, Christoph [1 ]
Zhu, Yingjun [1 ]
机构：
[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany
来源：
ORGANIC LETTERS | 2012年 / 14卷 / 07期
关键词：
DIRECT ARYLATIONS; ARYL CHLORIDES; COPPER; HETEROCYCLES; ACTIVATION; 1,3,4-OXADIAZOLES; BENZYLATIONS; CONSTRUCTION; PRELIGANDS; PARTNERS;
D O I：
10.1021/ol300514d
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium-catalyzed direct alkynylations of heteroarenes were accomplished with inexpensive gem-dichloroalkenes as user-friendly electrophiles, which set the stage for a modular, step-economical synthesis of diversely decorated heteroaryl alkynes with ample scope.
引用
收藏
页码：1824 / 1826
页数：3
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