Phase behaviour of polymer-grafted DPPC membranes for drug delivery systems design

被引：31
|
作者：
Pappalardo, M
Milardi, D
Grasso, D
La Rosa, C
机构：
[1] Univ Catania, Dipartimento Sci Chim, I-95125 Catania, Italy
[2] CNR, Sez Catania, Ist Biostrutture & Bioimmagini, I-95125 Catania, Italy
来源：
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY | 2005年 / 80卷 / 02期
关键词：
DPPC dispersions; drug delivery systems; phase behaviour; polymer grafted lipids;
D O I：
10.1007/s10973-005-0669-7
中图分类号：
O414.1 [热力学];
学科分类号：
摘要：
DPPC dispersions containing DPPE with attached PEG of molecular masses 350, 2000 and 5000 were investigated by DSC in order to determine their phase behaviour and potential use as drug delivery systems. In comparison with previously obtained ESR data, DSC provided a definition of the lipid composition and temperature at which the vesicles are in a liquid crystalline phase. For DPPC DPPE-PEG 350 the composition range is at molar fractions 0<(chi PEG350)< 0.5. For DPPC DPPE - PEG 2000 the range of applicability is 0<(chi PEG2000)< 0.07 and for DPPC/DPPE - PEG 5000 system it is 0<(chi PEG5000)< 0.05.
引用
收藏
页码：413 / 418
页数：6
相关论文
共 50 条
  • [31] Phase Behavior of Polymer-Grafted Nanoparticles in Homopolymer Blends from Simulations
    Santos, A. P.
    Frischknecht, Amalie L.
    MACROMOLECULES, 2022, 55 (23) : 10245 - 10254
  • [32] Polymer-grafted metal-organic frameworks: design, synthesis, and applications
    Yang, Xiaozhou
    Cheng, Tzu-Ching
    Morris, Amanda J.
    JOURNAL OF MATERIALS CHEMISTRY C, 2024, 12 (13) : 4562 - 4592
  • [33] Oil Encapsulation Advantages of Amphiphilic Polymer-Grafted Silica Nanoparticle Systems
    Keller, Christopher B.
    Siqueira, Julia S.
    Grayson, Scott M.
    ACS APPLIED POLYMER MATERIALS, 2021, 3 (11): : 5893 - 5902
  • [34] Polymer-Grafted Mesoporous Silica Nanoparticles as Ultrasound-Responsive Drug Carriers
    Paris, Juan L.
    Cabanas, M. Victoria
    Manzano, Miguel
    Vallet-Regi, Maria
    ACS NANO, 2015, 9 (11) : 11023 - 11033
  • [35] Shifts in chain-melting transition temperature of liposomal membranes by polymer-grafted lipids
    Pantusa, M
    Bartucci, R
    Marsh, D
    Sportelli, L
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2003, 1614 (02): : 165 - 170
  • [36] Polymer-Grafted Graphene Oxide/Polybenzimidazole Nanocomposites for Efficient Proton-Conducting Membranes
    Das, Anupam
    Mukherjee, Nilanjan
    Jana, Tushar
    ACS APPLIED NANO MATERIALS, 2023, 6 (07) : 6365 - 6379
  • [37] Characteristics of ultrafiltration membranes fabricated from polysulfone and polymer-grafted silica nanoparticles: Effects of the particle size and grafted polymer on the membrane performance
    Song, H. J.
    Jo, Y. J.
    Kim, Sang-Yoon
    Lee, Junseok
    Kim, C. K.
    JOURNAL OF MEMBRANE SCIENCE, 2014, 466 : 173 - 182
  • [38] Association of vasoactive intestinal peptide with polymer-grafted liposomes: Structural aspects for pulmonary delivery
    Stark, Brigitte
    Debbage, Paul
    Andreae, Fritz
    Mosgoeller, Wilhelm
    Prassl, Ruth
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2007, 1768 (03): : 705 - 714
  • [39] Dispersion, Phase Separation, and Self-Assembly of Polymer-Grafted Nanorod Composites
    Gollanapalli, Vaishnavi
    Manthri, Anirudh
    Sankar, Uma K.
    Tripathy, Mukta
    MACROMOLECULES, 2017, 50 (21) : 8816 - 8826
  • [40] Phase diagram of diblock copolymer confined in a cylindrical nanopore with polymer-grafted surface
    Li Ming
    Zhu Yue-Jin
    ACTA PHYSICA SINICA, 2008, 57 (12) : 7555 - 7564
12345