High Prevalence of High Grade Anal Intraepithelial Neoplasia in HIV-Infected Women Screened for Anal Cancer

被引：19
|
作者：
Hou, June Y. [1 ,2 ,3 ,4 ,5 ,6 ]
Smotkin, David [1 ,2 ,3 ,4 ,5 ,6 ]
Grossberg, Robert [1 ,2 ,3 ,4 ]
Suhrland, Mark [1 ,2 ,3 ,4 ]
Levine, Rebecca [1 ,2 ,3 ,4 ]
Smith, Harriet O. [1 ,2 ,3 ,4 ,5 ,6 ,7 ]
Negassa, Abdissa [5 ,6 ]
McAndrew, Thomas C. [5 ,6 ]
Einstein, Mark H. [1 ,2 ,3 ,4 ,5 ,6 ,7 ]
机构：
[1] Montefiore Med Ctr, Dept Obstet & Gynecol & Womens Hlth, Bronx, NY 10461 USA
[2] Montefiore Med Ctr, Dept Med, Bronx, NY 10461 USA
[3] Montefiore Med Ctr, Dept Pathol, Bronx, NY 10461 USA
[4] Montefiore Med Ctr, Dept Surg, Bronx, NY 10461 USA
[5] Albert Einstein Coll Med, Dept Obstet & Gynecol & Womens Hlth, Bronx, NY 10467 USA
[6] Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USA
[7] Albert Einstein Canc Ctr, Bronx, NY 10461 USA
来源：
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES | 2012年 / 60卷 / 02期
基金：
美国国家卫生研究院;
关键词：
anal cancer screening; anal cytology; high-resolution anoscopy; HPV-associated disease; LESIONS; CYTOLOGY; RISK; PERFORMANCE; POPULATION; ADULTS; MEN;
D O I：
10.1097/QAI.0b013e318251afd9
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
There is no consensus on optimal screening for anal cancer (AC) in HIV+ women. Seven hundred fifteen unique asymptomatic women in a high-prevalence HIV+ community were screened for AC with anal cytology and triage to high-resolution anoscopy after routine screening was implemented in a large urban hospital system. Of these, 75 (10.5%) had an abnormal anal cytology and 29 (38.7%) of those with an abnormality had high-grade anal intraepithelial neoplasia (AIN). Women with poorly controlled HIV were significantly more likely to have high-grade AIN (P = 0.03). Given the high rate of AIN in screened HIV-infected women, routine AC screening in all HIV-infected women should be strongly considered.
引用
收藏
页码：169 / 172
页数：4
相关论文
共 50 条
  • [21] High prevalence of human papillomavirus (HPV) infection and high-grade anal intraepithelial neoplasia in HIV-seropositive women, the EVVA study
    Coutlee, Francois
    Rodrigues-Coutlee, Sophie
    Munoz, Marie
    Mayrand, Marie Helene
    Charest, Louise
    Auger, Manon
    Marcus, Martin
    Burchell, Ann
    Klein, Marina
    De Castro, Christina
    Preziosi, Helen
    de Pokomandy, Alexandra
    SEXUAL HEALTH, 2013, 10 (06) : 573 - 573
  • [22] Progression of anal high-grade squamous intraepithelial lesions to invasive anal cancer among HIV-infected men who have sex with men
    Berry, J. Michael
    Jay, Naomi
    Cranston, Ross D.
    Darragh, Teresa M.
    Holly, Elizabeth A.
    Welton, Mark L.
    Palefsky, Joel M.
    INTERNATIONAL JOURNAL OF CANCER, 2014, 134 (05) : 1147 - 1155
  • [23] The effectiveness of electrocautery ablation for the treatment of high-grade anal intraepithelial neoplasia in HIV-infected men who have sex with men
    Burgos, J.
    Curran, A.
    Landolfi, S.
    Navarro, J.
    Tallada, N.
    Guelar, A.
    Crespo, M.
    Ocana, I.
    Ribera, E.
    Falco, V.
    HIV MEDICINE, 2016, 17 (07) : 524 - 531
  • [24] Malignant transformation of high-grade anal intraepithelial neoplasia
    Scholefield, JH
    Castle, MT
    Watson, NFS
    BRITISH JOURNAL OF SURGERY, 2005, 92 (09) : 1133 - 1136
  • [25] High-grade anal intraepithelial neoplasia: Progression to invasive cancer is not a certainty
    Gautier, Mathilde
    Brochard, Charlene
    Lion, Annie
    Henno, Sebastien
    Mallet, Anne Laure
    Bodere, Anais
    Bouguen, Guillaume
    Lievre, Astrid
    Siproudhis, Laurent
    DIGESTIVE AND LIVER DISEASE, 2016, 48 (07) : 806 - 811
  • [26] Trends in incidence and survival from anal cancer and incidence of high-grade anal intraepithelial neoplasia in Denmark
    Urbute, Aivara
    Munk, Christian
    Sand, Freja L.
    Belmonte, Federica
    Kjaer, Susanne K.
    CANCER EPIDEMIOLOGY, 2022, 77
  • [27] Trends in incidence of anal cancer and high-grade anal intraepithelial neoplasia in Denmark, 1978-2008
    Nielsen, Ann
    Munk, Christian
    Kjaer, Susanne K.
    INTERNATIONAL JOURNAL OF CANCER, 2012, 130 (05) : 1168 - 1173
  • [28] High prevalence of anal and cervical dysplasia in a cohort of HIV-infected women, but low prevalence of concomitant lesions
    Gomez, A.
    Revollo, B.
    Clotet, B.
    Sirera, G.
    Pares, D.
    Corral, J.
    Abad, I.
    Videla, S.
    HIV MEDICINE, 2019, 20 : 176 - 177
  • [29] Progression to and spontaneous regression of high-grade anal squamous intraepithelial lesions in HIV-infected and uninfected men
    Tong, Winnie W. Y.
    Jin, Fengyi
    McHugh, Leo C.
    Maher, Tara
    Sinclair, Brett
    Grulich, Andrew E.
    Hillman, Richard J.
    Carr, Andrew
    AIDS, 2013, 27 (14) : 2233 - 2243
  • [30] HAART and Progression to High-Grade Anal Intraepithelial Neoplasia in Men Who Have Sex with Men and Are Infected with HIV
    de Pokomandy, Alexandra
    Rouleau, Danielle
    Ghattas, George
    Trottier, Helen
    Vezina, Sylvie
    Cote, Pierre
    Macleod, John
    Allaire, Guy
    Hadjeres, Rachid
    Franco, Eduardo L.
    Coutlee, Francois
    CLINICAL INFECTIOUS DISEASES, 2011, 52 (09) : 1174 - 1181
12345