Novel Deuterated Gemini-vitamin D3 analogs have potent antitumor activity

被引:0
|
作者
Okamoto, Rvoko [1 ]
Saito, Tsuyako [1 ]
Haritunians, Talin [1 ]
O'Kelly, James [1 ]
Uskokovic, Milan [2 ]
Koeffler, H. Phillip [1 ]
机构
[1] Univ Calif Los Angeles, Sch Med, Cedars Sinai Med Ctr, Div Hematol & Oncol, Los Angeles, CA USA
[2] BioXell Inc, Nutley, NJ USA
关键词
D O I
10.1182/blood.V110.11.4210.4210
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
4210
引用
收藏
页码:120B / 120B
页数:1
相关论文
共 50 条
  • [31] Synthesis and evaluation of vitamin D3 analogs as Hedgehog pathway inhibitors
    Banerjee, Upasana
    Hadden, M. Kyle
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
  • [32] Vitamin D3 analogs stimulate hair growth in nude mice
    Vegesna, V
    O'Kelly, J
    Uskokovic, M
    Said, J
    Lemp, N
    Saitoh, T
    Ikezoe, T
    Binderup, L
    Koeffler, HP
    ENDOCRINOLOGY, 2002, 143 (11) : 4389 - 4396
  • [33] Transcriptional activation of the wild-type and mutant vitamin D receptors by vitamin D3 analogs
    Futawaka, Kumi
    Tagami, Tetsuya
    Fukuda, Yuki
    Koyama, Rie
    Nushida, Ayaka
    Nezu, Shoko
    Yamamoto, Hironori
    Imamoto, Miyuki
    Kasahara, Masato
    Moriyama, Kenji
    JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2016, 57 (01) : 23 - 32
  • [34] Gene expression profile changes induced by a novel Gemini vitamin D3 analog during the progression of breast cancer
    Lee, Hong Jin
    Liu, Hao
    Goodman, Catherine
    Ji, Yan
    Maehr, Hubert
    Uskokovic, Milan
    Notterman, Daniel
    Reiss, Michael
    Suh, Nanjoo
    CANCER RESEARCH, 2006, 66 (08)
  • [35] Inhalation with Vitamin D3 Metabolites-A Novel Strategy to Restore Vitamin D3 Deficiencies in Lung Tissue
    Chojnacki, Michal
    Anisiewicz, Jakub
    Lesniowska, Ilona
    Lemieszek, Marta Kinga
    APPLIED SCIENCES-BASEL, 2023, 13 (19):
  • [36] Immunomodulation by a novel, dissociated Vitamin D3 analogue
    Zuegel, Ulrich
    Steinmeyer, Andreas
    May, Ekkehard
    Lehmann, Manfred
    Asadullah, Khusru
    EXPERIMENTAL DERMATOLOGY, 2009, 18 (07) : 619 - 627
  • [38] Design, Synthesis and in vitro Antitumor Activity of Novel Actinomycin D Analogs
    Zhang Bang-Zhi
    Wang Kai-Rong
    Wang Ze-Zhou
    Li Xin-Lei
    Wang Xiao-Li
    Ni Jing-Man
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2010, 31 (07): : 1346 - 1352
  • [39] 1α-hydroxy 3-epi-vitamin D3:: A potent suppressor of PTH with low calcemic activity.
    Brown, AJ
    Ritter, CS
    Martin, DR
    Uskokovic, MR
    Reddy, GS
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2003, 14 : 201A - 202A
  • [40] An evaluation of the biologic activity and vitamin D receptor binding affinity of the photoisomers of vitamin D3, previtamin D3 and their hydroxylated derivatives
    Chen, TC
    Persons, KS
    Lu, ZR
    Mathieu, JS
    Holick, MF
    BIOLOGIC EFFECTS OF LIGHT 1998, 1999, : 145 - 148