Novel Deuterated Gemini-vitamin D3 analogs have potent antitumor activity

被引:0
|
作者
Okamoto, Rvoko [1 ]
Saito, Tsuyako [1 ]
Haritunians, Talin [1 ]
O'Kelly, James [1 ]
Uskokovic, Milan [2 ]
Koeffler, H. Phillip [1 ]
机构
[1] Univ Calif Los Angeles, Sch Med, Cedars Sinai Med Ctr, Div Hematol & Oncol, Los Angeles, CA USA
[2] BioXell Inc, Nutley, NJ USA
关键词
D O I
10.1182/blood.V110.11.4210.4210
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
4210
引用
收藏
页码:120B / 120B
页数:1
相关论文
共 50 条
  • [21] Extrarenal Vitamin D Activation and Interactions Between Vitamin D2, Vitamin D3, and Vitamin D Analogs
    Jones, Glenville
    ANNUAL REVIEW OF NUTRITION, VOL 33, 2013, 33 : 23 - 44
  • [22] C-20 cyclopropyl vitamin D3 analogs
    Uskokovic, Milan R.
    Manchand, Percy
    Marczak, Stanislaw
    Maehr, Hubert
    Jankowski, Pawel
    Adorini, Luciano
    Reddy, G. Satyanarayana
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2006, 6 (12) : 1289 - 1296
  • [23] Enhancement by other compounds of the anti-cancer activity of vitamin D3 and its analogs
    Danilenko, M
    Studzinski, GP
    EXPERIMENTAL CELL RESEARCH, 2004, 298 (02) : 339 - 358
  • [24] Antifibrogenic activities of novel vitamin D3 analogs are dependent on VDR expression in human fibroblasts
    Janjetovic, Z.
    Tuckey, R. C.
    Postlethwaite, A.
    Slominski, A. T.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2019, 139 (05) : S168 - S168
  • [25] METABOLITES OF VITAMIN D3 AND THEIR BIOLOGIC ACTIVITY
    PONCHON, G
    DELUCA, HF
    JOURNAL OF NUTRITION, 1969, 99 (02): : 157 - &
  • [26] Superagonistic Fluorinated Vitamin D3 Analogs Stabilize Helix 12 of the Vitamin D Receptor
    Eelen, Guy
    Valle, Noelia
    Sato, Yoshiteru
    Rochel, Natacha
    Verlinden, Lieve
    De Clercq, Pierre
    Moras, Dino
    Bouillon, Roger
    Munoz, Alberto
    Verstuyf, Annemieke
    CHEMISTRY & BIOLOGY, 2008, 15 (10): : 1029 - 1034
  • [27] An evaluation of the biologic activity and vitamin D receptor binding affinity of the photoisomers of vitamin D3 and previtamin D3
    Chen, TC
    Persons, KS
    Lu, ZR
    Mathieu, JS
    Holick, MF
    JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2000, 11 (05): : 267 - 272
  • [29] Enhanced transcriptional activity of novel gemini analogs of 1,25 dihydroxyvitamin D3:: Cellular actions suggest enhanced metabolic stability.
    Weyts, FAA
    Dhawan, P
    Tibrewal, N
    Zhang, X
    Bishop, JE
    Uskokovic, M
    Maehr, H
    Norman, AW
    Christakos, S
    JOURNAL OF BONE AND MINERAL RESEARCH, 2003, 18 : S296 - S296
  • [30] Antitumor action of interleukin-12, retinoids and vitamin D3 as related to their antiangiogenic activity.
    Majewski, S
    Marczak, M
    Szmurlo, A
    Nowicka, D
    Wrobel, A
    Bollag, W
    Jablonska, S
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1996, 107 (03) : 89 - 89