(Z)-Ethyl 2-cyano-2-{2-[5,6-dimethyl-4-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]hydrazinylidene}acetate

被引：2

作者：

Fun, Hoong-Kun ^{[1
]}

Hemamalini, Madhukar ^{[1
]}

Abdel-Aziz, Hatem A. ^{[2
]}

Aboul-Fadl, Tarek ^{[2
]}

机构：

[1] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, Usm 11800, Penang, Malaysia

[2] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2011年 / 67卷

关键词：

COX-2; 1,3,4-THIADIAZOLE; DERIVATIVES; INHIBITORS; POTENT;

D O I：

10.1107/S1600536811028911

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

In the title compound, C17H16N6O2S, an intramolecular N-H center dot center dot center dot O interaction generates an S(6) ring. The pyridine ring makes a dihedral angle of 71.38 (11)degrees with the thiophene ring. In the crystal, molecules are linked by a pair of N-H center dot center dot center dot N hydrogen bonds, forming an inversion dimer. The dimers are stacked in columns along the b axis through weak intermolecular C-H center dot center dot center dot N hydrogen bonds.

引用

页码：O2145 / U1509

页数：12

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