(Z)-Ethyl 2-cyano-2-{2-[5,6-dimethyl-4-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]hydrazinylidene}acetate

被引：2
|
作者：
Fun, Hoong-Kun [1 ]
Hemamalini, Madhukar [1 ]
Abdel-Aziz, Hatem A. [2 ]
Aboul-Fadl, Tarek [2 ]
机构：
[1] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, Usm 11800, Penang, Malaysia
[2] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2011年 / 67卷
关键词：
COX-2; 1,3,4-THIADIAZOLE; DERIVATIVES; INHIBITORS; POTENT;
D O I：
10.1107/S1600536811028911
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
In the title compound, C17H16N6O2S, an intramolecular N-H center dot center dot center dot O interaction generates an S(6) ring. The pyridine ring makes a dihedral angle of 71.38 (11)degrees with the thiophene ring. In the crystal, molecules are linked by a pair of N-H center dot center dot center dot N hydrogen bonds, forming an inversion dimer. The dimers are stacked in columns along the b axis through weak intermolecular C-H center dot center dot center dot N hydrogen bonds.
引用
收藏
页码：O2145 / U1509
页数：12
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