Enhanced efficacy of selumetinib by pretreatment of 5-FU in preclinical Ras/Raf-mutant colorectal cancer models

被引：0
|
作者：
Jang, Hye Yeon
Lee, Haeng Jung
Nam, Yeo Jin
Kim, Won Dong
Bae, Yong Ju
Jung, Jin Hwang
Lee, Seung Jin
Moon, Dae Hyuk
机构：
来源：
CANCER RESEARCH | 2017年 / 77卷
关键词：
D O I：
10.1158/1538-7445.AM2017-1204
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1204
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Molecular epidemiology of RAS/RAF-mutant colorectal cancer metastases
    Atreya, Chloe Evelyn
    Watters, James
    Rowley, Steve
    Lee, Joon Sang
    Iartchouk, Oleg
    Light, Madelyn
    Warren, Robert S.
    Venook, Alan Paul
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (03)
  • [2] Preclinical efficacy of carfilzomib in BRAF-mutant colorectal cancer models
    Maione, Federica
    Oddo, Daniele
    Galvagno, Federica
    Falcomata, Chiara
    Pandini, Marta
    Macagno, Marco
    Pessei, Valeria
    Barault, Ludovic
    Gigliotti, Chiara
    Mira, Alessia
    Corti, Giorgio
    Lamba, Simona
    Riganti, Chiara
    Castella, Barbara
    Massaia, Massimo
    Rad, Roland
    Saur, Dieter
    Bardelli, Alberto
    Di Nicolantonio, Federica
    MOLECULAR ONCOLOGY, 2024, 18 (06) : 1552 - 1570
  • [3] Perifosine potentiates 5-FU and oxaliplatin cytotoxicity in PIK3CA mutant colorectal cancer
    Takefuji, Honoka
    Tsubaki, Masanobu
    Takeda, Tomoya
    Takimoto, Koudai
    Nishida, Shozo
    CANCER SCIENCE, 2024, 115 : 651 - 651
  • [4] Oral intestinal alkaline phosphatase improves efficacy of 5-FU in a colorectal cancer mouse model
    Freguia, C. Furlan
    Kaleko, M.
    ANNALS OF ONCOLOGY, 2019, 30 : 764 - 764
  • [5] Preclinical Activity of the Rational Combination of Selumetinib (AZD6244) in Combination with Vorinostat in KRAS-Mutant Colorectal Cancer Models
    Pia Morelli, M.
    Tentler, John J.
    Kulikowski, Gillian N.
    Tan, Aik-Choon
    Bradshaw-Pierce, Erica L.
    Pitts, Todd M.
    Brown, Amy M.
    Nallapareddy, Sujatha
    Arcaroli, John J.
    Serkova, Natalie J.
    Hidalgo, Manuel
    Ciardiello, Fortunato
    Gail Eckhardt, S.
    CLINICAL CANCER RESEARCH, 2012, 18 (04) : 1051 - 1062
  • [6] Combination of ZD55-MnSOD therapy with 5-FU enhances antitumor efficacy in colorectal cancer
    Zhang, Yiqun
    Qin, Xinyu
    Zhang, Yanhong
    Zhao, Lili
    Wang, Yigang
    Liu, Xinyuan
    Yao, Liqing
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2008, 134 (02) : 219 - 226
  • [7] Prognostic markers to predict efficacy of 5-FU rechallenge as third line chemotherapy in metastatic colorectal cancer
    Chung, I. -J.
    Kim, K.
    Shim, H. -J.
    Hwang, J. -E.
    Bae, W. K.
    Cho, S. -H.
    ANNALS OF ONCOLOGY, 2016, 27 : 8 - 8
  • [8] Effects of polymorphisms in the MTHFR gene on 5-FU hematological toxicity and efficacy in Thai colorectal cancer patients
    Atasilp, Chalirmporn
    Lenavat, Rinradee
    Vanwong, Natchaya
    Chansriwong, Phichai
    Sirachainan, Ekaphop
    Reungwetwattana, Thanyanan
    Jinda, Pimonpan
    Aiempradit, Somthawin
    Sirilerttrakul, Suwannee
    Chamnanphon, Monpat
    Puangpetch, Apichaya
    Sankuntaw, Nipaporn
    Satapornpong, Patompong
    Sukasem, Chonlaphat
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [9] Combination of ZD55-MnSOD therapy with 5-FU enhances antitumor efficacy in colorectal cancer
    Yiqun Zhang
    Xinyu Qin
    Yanhong Zhang
    Lili Zhao
    Yigang Wang
    Xinyuan Liu
    Liqing Yao
    Journal of Cancer Research and Clinical Oncology, 2008, 134 : 219 - 226
  • [10] VRK2 promotes colorectal cancer growth and impedes immunotherapy and 5-FU treatment efficacy
    Wu, Yu-Tong
    Gao, Meng
    Cheng, Kun-Yang
    Li, Le
    Wang, Bai-Qi
    He, Ya-Nan
    Zhang, Yue
    Liu, Xue-Yi
    Du, Run-Lei
    Li, Guo-Qing
    Liang, Yue-Xiu
    Zhang, Jian-Feng
    Zhang, Xiao-Dong
    Liu, Yi
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2025, 1871 (04):
12345