Defective axonal transport increases Aβ production downstream from kinesin-1-assisted phosphorylation of amyloid-β precursor protein by JNK

被引：0
|
作者：
Muresan, V. [1 ]
Muresan, Z. Ladescu [1 ]
机构：
[1] Rutgers State Univ, New Jersey Med Sch, Pharmacol & Physiol, Newark, NJ 07102 USA
来源：
MOLECULAR BIOLOGY OF THE CELL | 2014年 / 25卷
关键词：
D O I：
暂无
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
P951
引用
收藏
页数：2
相关论文
共 42 条
  • [1] Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: Revisited
    Lazarov, O
    Morfini, GA
    Lee, EB
    Farah, MH
    Szodorai, A
    DeBoer, SR
    Koliatsos, VE
    Kins, S
    Lee, VMY
    Wong, PC
    Price, DL
    Brady, ST
    Sisodia, SS
    JOURNAL OF NEUROSCIENCE, 2005, 25 (09): : 2386 - 2395
  • [2] Decoupling the Effects of the Amyloid Precursor Protein From Amyloid-β Plaques on Axonal Transport Dynamics in the Living Brain
    Medina, Christopher S.
    Uselman, Taylor W.
    Barto, Daniel R.
    Chaves, Frances
    Jacobs, Russell E.
    Bearer, Elaine L.
    FRONTIERS IN CELLULAR NEUROSCIENCE, 2019, 13
  • [3] Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production
    Vagnoni, Alessio
    Perkinton, Michael S.
    Gray, Emma H.
    Francis, Paul T.
    Noble, Wendy
    Miller, Christopher C. J.
    HUMAN MOLECULAR GENETICS, 2012, 21 (13) : 2845 - 2854
  • [4] A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1
    Inomata, H
    Nakamura, Y
    Hayakawa, A
    Takata, H
    Suzuki, T
    Miyazawa, K
    Kitamura, N
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (25) : 22946 - 22955
  • [5] Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
    Kamal, A
    Stokin, GB
    Yang, ZH
    Xia, CH
    Goldstein, LSB
    NEURON, 2000, 28 (02) : 449 - 459
  • [6] Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
    Kamal, A
    Stokin, GB
    Xia, CH
    Goldstein, LSB
    MOLECULAR BIOLOGY OF THE CELL, 2000, 11 : 78A - 78A
  • [7] The role of amyloid precursor protein in kinesin-mediated axonal transport of presenilin-1 and beta-secretase
    Kamal, A
    Almenar-Queralt, A
    LeBlanc, JF
    Roberts, EA
    Goldstein, LSB
    MOLECULAR BIOLOGY OF THE CELL, 2001, 12 : 265A - 265A
  • [8] Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer's disease and regulates axonal transport and processing of the amyloid precursor protein
    Morotz, Gabor M.
    Glennon, Elizabeth B.
    Greig, Jenny
    Lau, Dawn H. W.
    Bhembre, Nishita
    Mattedi, Francesca
    Muschalik, Nadine
    Noble, Wendy
    Vagnoni, Alessio
    Miller, Christopher C. J.
    ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2019, 7 (01) : 200
  • [9] Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer’s disease and regulates axonal transport and processing of the amyloid precursor protein
    Gábor M. Mórotz
    Elizabeth B. Glennon
    Jenny Greig
    Dawn H. W. Lau
    Nishita Bhembre
    Francesca Mattedi
    Nadine Muschalik
    Wendy Noble
    Alessio Vagnoni
    Christopher C. J. Miller
    Acta Neuropathologica Communications, 7
  • [10] Netrin-1 interacts with amyloid precursor protein and regulates amyloid-β production
    F C Lourenço
    V Galvan
    J Fombonne
    V Corset
    F Llambi
    U Müller
    D E Bredesen
    P Mehlen
    Cell Death & Differentiation, 2009, 16 : 655 - 663
12345