Antioxidant, Cytotoxic and larvicidal Potential in Oxalis latifolia Kunth. Methanolic Leaf Extract

被引：0

作者：

Krishnan, R. Gopi ^{[1
]}

Murugesh, S. ^{[1
]}

机构：

[1] Periyar Univ, Sch Life Sci, Dept Bot, Salem 63601, India

来源：

JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL | 2021年 / 33卷 / 46A期

关键词：

Larvicidal potential; HT-29; Cx; quinquefasciatus; H2O2;

D O I：

10.9734/JPRI/2021/v33i46A32866

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Aims: The current work was analyzed in antioxidants, cytotoxicity and larvicidal potential were examined for O. latifolia methanolic leaf extract. Methodology: Antioxidant assasy for Hydroxyl radical (H2O2). Cytotoxicity potential was studied against colon (HT-29). Culex quinquefasciatus (IVth instar) larvae was used for larvicidal test. Results: Antioxidant and cytotoxicity exhibits significant activities with IC50 value of 442.94 mu g/mL and also the cytotoxicity activity IC50 values of 50.00 mu g/mL for HT-29. Larval mortality against the larvae of Cx. quinquefasciatus showed best activity with LC50 09.50mg/L and LC90 28.72 mg/L. Conclusion: Thus, this study proved that methanolic leaf extracts of O. latifolia have significant biological activities. Hence, it can be used for pharmacetutical applications.

引用

页码：269 / 275

页数：7

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