Antioxidant, Cytotoxic and larvicidal Potential in Oxalis latifolia Kunth. Methanolic Leaf Extract

被引：0
|
作者：
Krishnan, R. Gopi [1 ]
Murugesh, S. [1 ]
机构：
[1] Periyar Univ, Sch Life Sci, Dept Bot, Salem 63601, India
来源：
JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL | 2021年 / 33卷 / 46A期
关键词：
Larvicidal potential; HT-29; Cx; quinquefasciatus; H2O2;
D O I：
10.9734/JPRI/2021/v33i46A32866
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Aims: The current work was analyzed in antioxidants, cytotoxicity and larvicidal potential were examined for O. latifolia methanolic leaf extract. Methodology: Antioxidant assasy for Hydroxyl radical (H2O2). Cytotoxicity potential was studied against colon (HT-29). Culex quinquefasciatus (IVth instar) larvae was used for larvicidal test. Results: Antioxidant and cytotoxicity exhibits significant activities with IC50 value of 442.94 mu g/mL and also the cytotoxicity activity IC50 values of 50.00 mu g/mL for HT-29. Larval mortality against the larvae of Cx. quinquefasciatus showed best activity with LC50 09.50mg/L and LC90 28.72 mg/L. Conclusion: Thus, this study proved that methanolic leaf extracts of O. latifolia have significant biological activities. Hence, it can be used for pharmacetutical applications.
引用
收藏
页码：269 / 275
页数：7
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