Plant sterols and risk of stomach cancer: A case-control study in Uruguay

被引：80
|
作者：
De Stefani, E [1 ]
Boffetta, P
Ronco, AL
Brennan, P
Deneo-Pellegrini, H
Carzoglio, JC
Mendilaharsu, M
机构：
[1] Registro Nacl Canc, Montevideo, Uruguay
[2] Int Agcy Res Canc, Unit Environm Canc Epidemiol, F-69372 Lyon, France
来源：
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL | 2000年 / 37卷 / 02期
关键词：
D O I：
10.1207/S15327914NC372_4
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In 1997-1999, 120 incident and histologically verified cases of stomach cancer were frequency matched on age, gender, residence, and urban/rural status wish 360 controls to study the role of diet in gastric cancer in Uruguay. We focused on the role of plant sterols (beta -sitosterol, campesterol, stigmasterol, and total plant sterols) after controlling for major confounders. Total phytosterols were associated with a strong inverse relationship with stomach cancer (odds ratio of stomach cancer for total phytosrerol intake in the highest tertile = 0.33, 95% confidence interval = 0.17-0.65) Joins exposure so high intake of total phytosterol and alpha -carotene was also inversely associated with gastric cancer risk (odds ratio = 0.09, 95% confidence interval = 0.02-0.32). High intake of total plant sterols explained most of the attenuation in risk of gastric cancer associated with vegetable and fruit intakes.
引用
收藏
页码：140 / 144
页数：5
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