Plant sterols and risk of stomach cancer: A case-control study in Uruguay

被引:81
|
作者
De Stefani, E [1 ]
Boffetta, P
Ronco, AL
Brennan, P
Deneo-Pellegrini, H
Carzoglio, JC
Mendilaharsu, M
机构
[1] Registro Nacl Canc, Montevideo, Uruguay
[2] Int Agcy Res Canc, Unit Environm Canc Epidemiol, F-69372 Lyon, France
来源
关键词
D O I
10.1207/S15327914NC372_4
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In 1997-1999, 120 incident and histologically verified cases of stomach cancer were frequency matched on age, gender, residence, and urban/rural status wish 360 controls to study the role of diet in gastric cancer in Uruguay. We focused on the role of plant sterols (beta -sitosterol, campesterol, stigmasterol, and total plant sterols) after controlling for major confounders. Total phytosterols were associated with a strong inverse relationship with stomach cancer (odds ratio of stomach cancer for total phytosrerol intake in the highest tertile = 0.33, 95% confidence interval = 0.17-0.65) Joins exposure so high intake of total phytosterol and alpha -carotene was also inversely associated with gastric cancer risk (odds ratio = 0.09, 95% confidence interval = 0.02-0.32). High intake of total plant sterols explained most of the attenuation in risk of gastric cancer associated with vegetable and fruit intakes.
引用
收藏
页码:140 / 144
页数:5
相关论文
共 50 条
  • [21] Dietary fiber and risk of breast cancer: A case-control study in Uruguay
    DeStefani, E
    Correa, P
    Ronco, A
    Mendilaharsu, M
    Guidobono, M
    DeneoPellegrini, H
    [J]. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 1997, 28 (01): : 14 - 19
  • [22] Risk Factors for Premenopausal Breast Cancer: A Case-control Study in Uruguay
    Ronco, Alvaro L.
    De Stefani, Eduardo
    Deneo-Pellegrini, Hugo
    [J]. ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2012, 13 (06) : 2879 - 2886
  • [23] Dietary patterns and risk of gastric cancer: A case-control study in Uruguay
    De Stefani E.
    Correa P.
    Boffetta P.
    Deneo-Pellegrini H.
    Ronco A.L.
    Mendilaharsu M.
    [J]. Gastric Cancer, 2004, 7 (4) : 211 - 220
  • [24] ESOPHAGEAL CANCER IN URUGUAY - A CASE-CONTROL STUDY
    VASSALLO, A
    CORREA, P
    DESTEFANI, E
    CENDAN, M
    ZAVALA, D
    CHEN, V
    CARZOGLIO, J
    DENEOPELLEGRINI, H
    [J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1985, 75 (06) : 1005 - 1009
  • [25] Meat, fat and risk of breast cancer: A case-control study from Uruguay
    Ronco, A
    DeStefani, E
    Mendilaharsu, M
    DeneoPellegrini, H
    [J]. INTERNATIONAL JOURNAL OF CANCER, 1996, 65 (03) : 328 - 331
  • [26] Salted Meat Consumption and the Risk of Cancer: a Multisite Case-Control Study in Uruguay
    De Stefani, Eduardo
    Aune, Dagfinn
    Boffetta, Paolo
    Deneo-Pellegrini, Hugo
    Ronco, Alvaro L.
    Acosta, Gisele
    Brennan, Paul
    Ferro, Gilles
    Mendilaharsu, Maria
    [J]. ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2009, 10 (05) : 853 - 857
  • [27] Dietary nitrosodimethylamine and the risk of lung cancer: A case-control study from Uruguay
    DeStefani, E
    DeneoPellegrini, H
    Carzoglio, JC
    Ronco, A
    Mendilaharsu, M
    [J]. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 1996, 5 (09) : 679 - 682
  • [28] Diabetes, Overweight and Risk of Postmenopausal Breast Cancer: A Case-Control Study in Uruguay
    Ronco, Alvaro L.
    De Stefani, Eduardo
    Deneo-Pellegrini, Hugo
    Quarneti, Aldo
    [J]. ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2012, 13 (01) : 139 - 146
  • [29] Dietary acid load and breast cancer risk: A case-control study in Uruguay
    Ronco, A.
    Calderon, J.
    Mendoza, B.
    [J]. EUROPEAN JOURNAL OF CANCER, 2020, 138 : S122 - S122
  • [30] Fatty foods and the risk of lung cancer: A case-control study from Uruguay
    DeStefani, E
    Fontham, ETH
    Chen, VV
    Correa, P
    DeneoPellegrini, H
    Ronco, A
    Mendilaharsu, M
    [J]. INTERNATIONAL JOURNAL OF CANCER, 1997, 71 (05) : 760 - 766