In 1997-1999, 120 incident and histologically verified cases of stomach cancer were frequency matched on age, gender, residence, and urban/rural status wish 360 controls to study the role of diet in gastric cancer in Uruguay. We focused on the role of plant sterols (beta -sitosterol, campesterol, stigmasterol, and total plant sterols) after controlling for major confounders. Total phytosterols were associated with a strong inverse relationship with stomach cancer (odds ratio of stomach cancer for total phytosrerol intake in the highest tertile = 0.33, 95% confidence interval = 0.17-0.65) Joins exposure so high intake of total phytosterol and alpha -carotene was also inversely associated with gastric cancer risk (odds ratio = 0.09, 95% confidence interval = 0.02-0.32). High intake of total plant sterols explained most of the attenuation in risk of gastric cancer associated with vegetable and fruit intakes.
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Registro Nacional de Cáncer, MontevideoRegistro Nacional de Cáncer, Montevideo
De Stefani E.
Correa P.
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Department of Pathology, Louisiana State University, Medical Center, New Orleans, LARegistro Nacional de Cáncer, Montevideo
Correa P.
Boffetta P.
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U. of Environ. Cancer Epidemiology, Intl. Agency for Research on Cancer, Lyon
Division of Clinical Epidemiology, German Cancer Research Center (DKFZ), HeidelbergRegistro Nacional de Cáncer, Montevideo
Boffetta P.
Deneo-Pellegrini H.
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Registro Nacional de Cáncer, MontevideoRegistro Nacional de Cáncer, Montevideo
Deneo-Pellegrini H.
Ronco A.L.
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Registro Nacional de Cáncer, MontevideoRegistro Nacional de Cáncer, Montevideo
Ronco A.L.
Mendilaharsu M.
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Registro Nacional de Cáncer, MontevideoRegistro Nacional de Cáncer, Montevideo