Sesquiterpenes from the roots of Lindera strychnifolia with inhibitory effects on nitric oxide production in RAW 264.7 cells

被引：11

作者：

Liu, Qing ^{[1
]}

Jo, Yang Hee ^{[1
]}

Kim, Seon Beom ^{[1
]}

Jin, Qinghao ^{[1
]}

Hwang, Bang Yeon ^{[1
]}

Lee, Mi Kyeong ^{[1
]}

机构：

[1] Chungbuk Natl Univ, Coll Pharm, Chongju 28644, South Korea

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2016年 / 26卷 / 20期

基金：

新加坡国家研究基金会;

关键词：

Lindera strychnifolia; Lauraceae; Sesquiterpene; Linderolides N-T; Anti-inflammation; CORAL MENELLA SP; NEOLITSEA-PARVIGEMMA; IN-VITRO; INFLAMMATION; LACTONES; RESOLUTION; SYNTHASE; EXTRACT;

D O I：

10.1016/j.bmcl.2016.09.012

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Seven new sesquiterpenes, linderolides N-T (1-7), along with nine known compounds, were isolated from roots of Lindera strychnifolia (Lauraceae). Their structures were established by extensive spectroscopic analysis. The relative and absolute configurations were determined by NOESY and CD analysis, respectively. Among the isolated compounds, two new compounds, linderolide O (2) and linderolide P (3) inhibited lipopolysaccharide-stimulated nitric oxide production in murine RAW 264.7 macrophage cells, with IC50 values of 6.3 and 9.6 mu M, respectively. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：4950 / 4954

页数：5

共 50 条

[21] The inhibitory action of quercetin on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells
Mu, MM
Chakravortty, D
Sugiyama, T
Koide, N
Takahashi, K
Mori, I
Yoshida, T
Yokochi, T
JOURNAL OF ENDOTOXIN RESEARCH, 2001, 7 (06): : 431 - 438
[22] Terpenoids from the roots ofLeontopodium longifoliumand their inhibitory activity on NO production in RAW264.7 cells
Shen, Tong
Qian, Han
Wang, Yong-Dong
Li, Hai-Bei
Xie, Wei-Dong
NATURAL PRODUCT RESEARCH, 2020, 34 (16) : 2323 - 2327
[23] Inhibition of nitric oxide production in RAW 264.7 cells by azaphilones from xylariaceous fungi
Quang, DN
Harinantenaina, L
Nishizawa, T
Hashimoto, T
Kohchi, C
Soma, GI
Asakawa, Y
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2006, 29 (01) : 34 - 37
[24] Sesquiterpenes from the essential oil of Curcuma wenyujin and their inhibitory effects on nitric oxide production
Xia, Guiyang
Zhou, Li
Ma, Jianghao
Wang, Ying
Ding, Liqin
Zhao, Feng
Chen, Lixia
Qiu, Feng
FITOTERAPIA, 2015, 103 : 143 - 148
[25] New guaiane sesquiterpenes from Artemisia rupestris and their inhibitory effects on nitric oxide production
Hou, Jiqin
Dong, Huijun
Yan, Ming
Zhu, Fengyan
Zhang, Xiaoqi
Wang, Hao
Ye, Wencai
Li, Ping
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (18) : 4435 - 4438
[26] Lignan derivatives from Selaginella tamariscina and their nitric oxide inhibitory effects in LPS-stimulated RAW 264.7 cells
Le Duc Dat
Zhao, Bing Tian
Nguyen Duc Hung
Lee, Jeong Hyung
Min, Byung Sun
Woo, Mi Hee
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (03) : 524 - 529
[27] Inhibitory action of eugenol compounds on the production of nitric oxide in RAW264.7 macrophages
Li, Weihua
Tsubouchi, Ryoko
Qiao, Shanlou
Haneda, Miyako
Murakami, Keiko
Yoshino, Masataka
BIOMEDICAL RESEARCH-TOKYO, 2006, 27 (02): : 69 - 74
[28] Inhibitory constituents of the heartwood of Dalbergia odorifera on nitric oxide production in RAW 264.7 macrophages
Lee, Chul
Lee, Jin Woo
Jin, Qinghao
Jang, Dae Sik
Lee, Sung-Joon
Lee, Dongho
Hong, Jin Tae
Kim, Youngsoo
Lee, Mi Kyeong
Hwang, Bang Yeon
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (14) : 4263 - 4266
[29] Effects of endosulfan isomers on cytokine and nitric oxide production by differentially activated RAW 264.7 cells
Terry, Alexander I.
Benitez-Kruidenier, Sandra
DeKrey, Gregory K.
TOXICOLOGY REPORTS, 2018, 5 : 396 - 400
[30] Inhibitory effect of resveratrol dimerized derivatives on nitric oxide production in lipopolysaccharide-induced RAW 264.7 cells
Zhong, Chen
Liu, Xin-Hua
Chang, Jun
Yu, Jian-Ming
Sun, Xun
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (15) : 4413 - 4418

← 1 2 3 4 5 →